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18670 Abcb4

18670

Abcb4

ATP-binding cassette, sub-family B (MDR/TAP), member 4

protein-coding

Mus musculus

基因描述

Type Description
Definition ATP-binding cassette, sub-family B (MDR/TAP), member 4

研究结论

Date Results Publications
2021-04-17 13:12:00 The pro-oncogenic effect of the lncRNA H19 in the development of chronic inflammation-mediated hepatocellular carcinoma. 33093654
2021-03-06 13:29:00 Administration of Human MSC-Derived Extracellular Vesicles for the Treatment of Primary Sclerosing Cholangitis: Preclinical Data in MDR2 Knockout Mice. 33238629
2020-12-05 13:01:00 Knockout of the Tachykinin Receptor 1 in the Mdr2(-/-) (Abcb4(-/-)) Mouse Model of Primary Sclerosing Cholangitis Reduces Biliary Damage and Liver Fibrosis. 32712019
2020-05-30 11:28:00 Cholangiocytes, but not hepatocytes, from stem cell factor (SCF) Mismatch Mdr2(-/-) mice have increased SCF expression and secretion. Inhibition of SCF in Mdr2(-/-) mice reduced (i) hepatic damage; (ii) mast cell migration; (iii) histamine and SCF serum levels. 31521820
2020-03-07 12:29:00 Taurohyodeoxycholate strongly enhances biliary phosphatidylcholine (PC) secretion in Abcb4+/+ mice. Taurohyodeoxycholate has no effect on biliary PC secretion in Abcb4-/- mice. 31176036

名称对应

Type IDs
Synonymous Mdr2, Pgy-2, Pgy2, mdr-2
Gene
UniProtKB-ID: MDR3_MOUSE
UniprotKB: P21440
UniParc: UPI0000020D70
EMBL: J03398, CH466600, M74151, BC150687, U46839
Ensembl: ENSMUSG00000042476
KO: mmu:18670
Nucleutide sequences
EMBL-CDS: AAA39516.1, EDL14681.1, AAA39515.1, AAC52722.1, AAI50688.1
Ensembl_TRS: ENSMUST00000003717
Protein sequencees
Ensembl_PRO: ENSMUSP00000003717
RefSeq: XP_036020767.1, XP_006503615.1, XP_006503614.1, NP_032856.2, XP_006503617.1
Others
UniRef100: UniRef100_P21440
UniRef90: UniRef90_P21439-3
UniRef50: UniRef50_P21439
UniGene: Mm.297825
CCDS: CCDS19086.1

全选

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