| Type | Description |
|---|---|
| Definition | phosphoglycerate kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 10:54:00 | Not only did supplementary Pgk1 enhance neurite outgrowth of motoneurons in defective cells, but injection of Pgk1 rescued denervation in muscle-specific NogoA-overexpression of zebrafish and an Amyotrophic Lateral Sclerosis mouse model, SOD1 G93A. | 31361595 |
| 2017-06-03 11:28:00 | Pgk1 overexpression, or treatment with terazosin (an FDA-approved small molecule that binds and activates Pgk1), rescued motor axon phenotypes in SMA zebrafish. We conclude that global bioenergetics pathways can be therapeutically manipulated to ameliorate SMA motor neuron phenotypes in vivo. | 28426667 |
| 2014-01-31 08:53:00 | Phosphoglycerate kinase is a moonlighting protein that functions as both a glycolytic enzyme and a disulfide reductase. | 11130727 |
| 2012-09-22 10:09:00 | Purification and characterization of 3-phosphoglycerate kinase from Ehrlich ascites carcinoma cells | 22905379 |
| 2011-07-02 11:23:00 | PGK domain movement and catalysis is regulated by a spring-loaded release mechanism | 21349853 |
| Type | IDs |
|---|---|
| Synonymous | Pgk-1 |
| Gene |
UniProtKB-ID:
PGK1_MOUSE
UniprotKB:
P09411
UniParc:
UPI0000023706
EMBL:
X15339,
M15668,
M18735,
AK167710,
AK164440,
BX469914,
AK167441,
AK167459,
AK145846,
AK133877,
BC083355,
BC108372,
X55309
Ensembl:
ENSMUSG00000062070
KO:
mmu:18655
|
| Nucleutide sequences |
EMBL-CDS:
AAA70267.1,
BAE37790.1,
CAA33391.1,
BAE39527.1,
BAE39544.1,
CAA39013.1,
BAE26693.1,
BAE39754.1,
BAE21906.1,
AAI08373.1,
AAA39919.1,
AAH83355.1
Ensembl_TRS:
ENSMUST00000081593
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000080302
RefSeq:
NP_032854.2
|
| Others |
UniRef100:
UniRef100_P09411
UniRef90:
UniRef90_P00558
UniRef50:
UniRef50_P00558
UniGene:
Mm.336204,
Mm.336205
CCDS:
CCDS30339.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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