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18640 Pfkfb2

18640

Pfkfb2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

protein-coding

Mus musculus

基因描述

Type Description
Definition 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

研究结论

Date Results Publications
2021-04-13 10:14:00 HIF-1/AKT Signaling-Activated PFKFB2 Alleviates Cardiac Dysfunction and Cardiomyocyte Apoptosis in Response to Hypoxia. 33678793
2020-11-28 13:11:00 PP2Acalpha inhibits PFKFB2-induced glycolysis to promote termination of liver regeneration. 32192773
2018-07-21 10:47:00 In diabetes mellitus type 1 loss of myocardial PFK-2 content as a result of reduced insulin signaling impairs the capacity to dynamically regulate glycolysis and elevates the levels of early glycolytic intermediates. 29203581
2018-06-02 11:15:00 he dysfunction at disease onset was accompanied by increased expression of the rate-limiting glycolytic enzyme phosphofructokinase-2 in activated astrocytes, and by selective reduction in spinal mitochondrial complex I activity 27624721
2010-10-23 11:04:00 SGK3 is not required for insulin-induced PFK-2 activation and that this effect is likely mediated by PKBalpha. 20687898

名称对应

Type IDs
Synonymous 4930568D07Rik
Gene
UniProtKB-ID: F262_MOUSE, Q8CDS6_MOUSE, Q6GTL7_MOUSE, B2Z892_MOUSE, B2Z893_MOUSE
UniprotKB: P70265, Q8CDS6, Q6GTL7, B2Z892, B2Z893
UniParc: UPI00000228C9, UPI0001B04BE5, UPI00001ED5D8, UPI00000E91F2, UPI0001741F80
EMBL: AK029659, BC018418, AK146744, EU616667, EU616668, BC051014, X98847, AC139231
Ensembl: ENSMUSG00000026409
KO: mmu:18640
Nucleutide sequences
EMBL-CDS: CAA67352.1, AAH18418.1, BAC26551.1, BAE27404.1, AAH51014.1, ACC97555.1, ACC97556.1
Ensembl_TRS: ENSMUST00000169659, ENSMUST00000185233, ENSMUST00000066863, ENSMUST00000050406, ENSMUST00000189534, ENSMUST00000171479
Protein sequencees
Ensembl_PRO: ENSMUSP00000140551, ENSMUSP00000066426, ENSMUSP00000127587, ENSMUSP00000133073, ENSMUSP00000140355, ENSMUSP00000129747
RefSeq: NP_001155888.1, NP_001355772.1, NP_032851.2, NP_001155887.1
Others
UniRef100: UniRef100_P70265, UniRef100_B2Z893, UniRef100_Q8CDS6, UniRef100_Q6GTL7, UniRef100_B2Z892
UniRef90: UniRef90_Q9JJH5-3, UniRef90_Q9JJH5, UniRef90_G3T0W9
UniRef50: UniRef50_O60825
UniGene: Mm.249861

全选

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