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18618 Pemt

18618

Pemt

phosphatidylethanolamine N-methyltransferase

protein-coding

Mus musculus

基因描述

Type Description
Definition phosphatidylethanolamine N-methyltransferase

研究结论

Date Results Publications
2021-02-20 13:30:00 Methyl-Sensing Liver Receptor Homolog-1 Regulates Mitochondrial Function in Mouse Hepatocytes. 31355949
2021-01-02 12:48:00 Alternative splicing of UCP1 by non-cell-autonomous action of PEMT. 31918922
2020-12-12 13:28:00 Implication of phosphatidylethanolamine N-methyltransferase in adipocyte differentiation. 32502648
2017-09-09 13:32:00 fenofibrate partially reversed hepatic steatosis and fibrosis in Pemt(-/-) mice when treatment was initiated after nonalcoholic fatty liver disease (NAFLD) had already been established. Increasing hepatic fatty acid oxidation can compensate for the lower VLDL-triacylglycerol secretion rate and prevent/reverse fatty liver disease in mice lacking PEMT. 28159867
2017-09-02 12:23:00 Results show that hepatic PEMT protein levels and activity are post-translationally repressed in homocystinuria and correlates with decreased phosphatidylcholine. 28291718

名称对应

Type IDs
Synonymous PEAMT, PEMT2, PLMT, Pempt, Pempt2
Gene
UniProtKB-ID: PEMT_MOUSE
UniprotKB: Q61907
UniParc: UPI0000020A81, UPI0000470497
EMBL: BC026796, AK133744, U25046, U25047, U25048, AL645526, U25050, AL603710, U25051, U25049, AY334571
Ensembl: ENSMUSG00000000301
KO: mmu:18618
Nucleutide sequences
EMBL-CDS: AAQ01190.1, AAA67686.1, BAE21818.1, AAH26796.1
Ensembl_TRS: ENSMUST00000102693, ENSMUST00000000310, ENSMUST00000102692
Protein sequencees
Ensembl_PRO: ENSMUSP00000000310, ENSMUSP00000099754, ENSMUSP00000099753
RefSeq: NP_001276941.1, NP_001276940.1, XP_006532541.1, NP_001276943.1, NP_001276942.1, NP_032845.2
Others
UniRef100: UniRef100_Q61907
UniRef90: UniRef90_Q61907
UniRef50: UniRef50_Q61907
UniGene: Mm.2731
CCDS: CCDS78957.1, CCDS24782.1

全选

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