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18609 Pdx1

18609

Pdx1

pancreatic and duodenal homeobox 1

protein-coding

Mus musculus

基因描述

Type Description
Definition pancreatic and duodenal homeobox 1

研究结论

Date Results Publications
2021-02-02 13:27:00 Tectorigenin enhances PDX1 expression and protects pancreatic beta-cells by activating ERK and reducing ER stress. 32690606
2020-10-31 13:19:00 LncRNA MALAT1 induces the dysfunction of beta cells via reducing the histone acetylation of the PDX-1 promoter in type 1 diabetes. 32243891
2020-06-06 13:41:00 Findings indicate that intracellular stress caused by Pdx1 inactivation triggers the senescence-associated secretory phenotype to maintain organ homeostasis. 31240701
2020-04-18 10:07:00 PDX1 expression is maintained via the Erk pathway and protects islet beta-cells against glucotoxicity and lipotoxicity 31337977
2019-10-26 12:44:00 GPR120 activation is protective against lipotoxicity-induced pancreatic beta-cell dysfunction, by mediation of PDX1 expression and inhibition of islet inflammation. 30523046

名称对应

Type IDs
Synonymous IDX-1, IPF-1, Ipf1, Mody4, STF-1, pdx-1
Gene
UniProtKB-ID: PDX1_MOUSE
UniprotKB: P52946
UniParc: UPI0000003F44
EMBL: AK020261, X74342, BC103582, BC103572, BC105642, BC103581
Ensembl: ENSMUSG00000029644
KO: mmu:18609
Nucleutide sequences
EMBL-CDS: AAI05643.1, AAI03582.1, CAA52389.1, AAI03573.1, AAI03583.1, BAB32045.1
Ensembl_TRS: ENSMUST00000085591
Protein sequencees
Ensembl_PRO: ENSMUSP00000082729
RefSeq: NP_032840.1
Others
UniRef100: UniRef100_P52946
UniRef90: UniRef90_P52946
UniRef50: UniRef50_P52946
UniGene: Mm.389714
CCDS: CCDS39398.1

全选

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研究热度

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