| Type | Description |
|---|---|
| Definition | pyruvate dehydrogenase kinase, isoenzyme 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:55:00 | Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype. | 31134063 |
| 2017-12-02 10:52:00 | our results suggest that PDK2/4 can be a potential target for the development of pharmacotherapy for the treatment of acute inflammatory pain | 26931482 |
| 2017-05-20 13:46:00 | The current study reports that increasing hepatic PDC activity by inhibition of PDK2 ameliorates hepatic steatosis and insulin sensitivity by regulating TCA cycle anaplerosis and ketogenesis. The findings suggest PDK2 is a potential therapeutic target for nonalcoholic fatty liver disease. | 27385159 |
| 2016-08-13 11:55:00 | PDK2/4 induction and the subsequent lactate surge induce the metabolic shift in the diabetic dorsal root ganglion thereby contributing to the pathogenesis of painful diabetic neuropathy. | 26769971 |
| 2016-04-02 11:19:00 | These findings reveal that there are divergent roles of PDKs during oocyte maturation and indicate a new mechanism controlling meiotic structure. | 25991547 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PDK2_MOUSE
UniprotKB:
Q9JK42
UniParc:
UPI00000E89BD
EMBL:
AL606480,
BC021764,
CH466556,
AF267660
Ensembl:
ENSMUSG00000038967
KO:
mmu:18604
|
| Nucleutide sequences |
EMBL-CDS:
AAF72038.1,
EDL15963.1,
AAH21764.1
Ensembl_TRS:
ENSMUST00000038431
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041447
RefSeq:
NP_598428.2,
NP_001348844.1
|
| Others |
UniRef100:
UniRef100_Q9JK42
UniRef90:
UniRef90_Q9JK42
UniRef50:
UniRef50_Q15120
UniGene:
Mm.29768
CCDS:
CCDS25270.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员