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18602 Padi4

18602

Padi4

peptidyl arginine deiminase, type IV

protein-coding

Mus musculus

基因描述

Type Description
Definition peptidyl arginine deiminase, type IV

研究结论

Date Results Publications
2021-04-13 10:15:00 Peptidylarginine Deiminase 4 Promotes the Renal Infiltration of Neutrophils and Exacerbates the TLR7 Agonist-Induced Lupus Mice. 32655553
2020-02-01 10:43:00 exacerbates ischemic acute kidney injury and inflammation by promoting renal tubular NF-kappaB activity and inflammation via NEMO citrullination. 30943066
2019-10-12 11:11:00 Data suggest that mixed lineage kinase domain-like (MLKL) activation leads to loss of intracellular architecture and chromatin decondensation, but peptidylarginine deiminase 4 is only required for the externalization of neutrophil extracellular trap (NET). 30181240
2019-09-21 12:26:00 Our data support the notion that NETs promote atherosclerosis and that the use of specific inhibitors may have therapeutic benefits in this potentially devastating condition. 30140264
2019-09-07 11:34:00 Renal proximal tubular appears to contribute to ischemic acute kidney injury by promoting renal tubular apoptosis, whereas myeloid-cell duanyu15634 is preferentially involved in promoting neutrophil infiltration to the kidney and inflammation after renal ischemia/reperfusion. 29357426

名称对应

Type IDs
Synonymous Pad4, Pdi4
Gene
UniProtKB-ID: PADI4_MOUSE
UniprotKB: Q9Z183
UniParc: UPI000024DCCD
EMBL: AB121692, AL807805, AB013850
Ensembl: ENSMUSG00000025330
KO: mmu:18602
Nucleutide sequences
EMBL-CDS: BAD16627.1, BAA34246.1
Ensembl_TRS: ENSMUST00000026381
Protein sequencees
Ensembl_PRO: ENSMUSP00000026381
RefSeq: NP_035191.2
Others
UniRef100: UniRef100_Q9Z183
UniRef90: UniRef90_Q9Z183
UniRef50: UniRef50_Q9Z183
UniGene: Mm.250358
CCDS: CCDS18854.1

全选

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研究热度

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