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18588 Pde6g

18588

Pde6g

phosphodiesterase 6G, cGMP-specific, rod, gamma

protein-coding

Mus musculus

基因描述

Type Description
Definition phosphodiesterase 6G, cGMP-specific, rod, gamma

研究结论

Date Results Publications
2020-06-06 11:15:00 This study sheds new light on the versatility of tetratricopeptide repeat domain (TPR) domains in protein folding by describing a novel TPR-protein binding partner, Pgamma, and revealing that this subunit imparts AIPL1 selectivity for its client. 31488544
2017-05-13 10:23:00 AIPL1-mediated production of folded PDE6C is markedly elevated in the presence of the inhibitory Pgamma-subunit of PDE6. 27268253
2015-06-20 12:06:00 The presence of rod PDE6G in cones indicating functional substitution of PDE6h in mice. 25739440
2012-02-25 11:27:00 our results show for the first time that the Ile(86) and Ile(87) residues of PDE6-gamma are necessary for normal inhibition of PDE6 catalytic activity in vivo 21920434
2011-12-10 12:06:00 PDE6gamma is a major component of the photoresponse and is required to support rod integrity. 21616145

名称对应

Type IDs
Synonymous Pdeg, p3AT
Gene
UniProtKB-ID: CNRG_MOUSE, Q542R6_MOUSE
UniprotKB: P09174, Q542R6
UniParc: UPI0000000CF5
EMBL: AF190928, AK080735, BC082288, Y00746
Ensembl: ENSMUSG00000025386
KO: mmu:18588
Nucleutide sequences
EMBL-CDS: AAH82288.1, CAA68714.1, AAG17169.1, BAC38001.1
Ensembl_TRS: ENSMUST00000026452
Protein sequencees
Ensembl_PRO: ENSMUSP00000026452
RefSeq: NP_036197.1, XP_006532518.1
Others
UniRef100: UniRef100_P09174
UniRef90: UniRef90_P09174
UniRef50: UniRef50_Q13956
UniGene: Mm.39200
CCDS: CCDS36389.1

全选

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