| Type | Description |
|---|---|
| Definition | NAD-dependent protein deacylase sir-2.3 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-16 12:06:00 | we found that knock-out of mitochondrial sirtuin sir-2.3, homologous to mammalian SIRT4, is protective in both chemical ischemia and hyperactive channel induced necrosis. Furthermore, the protective effect of sir-2.3 knock-out is enhanced by block of glycolysis and eliminated by a null mutation in daf-16/FOXO transcription factor, supporting the involvement of the insulin/IGF pathway | 28820880 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SIR42_CAEEL
UniprotKB:
Q20481
UniParc:
UPI00000785B0
EMBL:
Z50177
EnsemblGenome:
WBGene00004802
KO:
cel:CELE_F46G10.3
|
| Nucleutide sequences |
EMBL-CDS:
CAA90547.1
Gene_ORFName:
F46G10.3
EnsemblGenome_TRS:
F46G10.3.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F46G10.3.1
RefSeq:
NP_510220.1
|
| Others |
UniRef100:
UniRef100_Q20481
UniRef90:
UniRef90_Q20481
UniRef50:
UniRef50_Q20481
UniGene:
Cel.993
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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