| Type | Description |
|---|---|
| Definition | phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide |
| Date | Results | Publications |
|---|---|---|
| 2019-09-14 11:59:00 | PKM2 can regulate transcriptional activity of PDE6B via its promoter in a mouse retinal degeneration model. | 29445082 |
| 2019-03-09 12:18:00 | Retinal degeneration was slowed down in Cngb1/Pde6b double knock-out mice due to lowering of cGMP content in the retinas, and suggests that it may be caused by mislocalization of active Pde6b. | 30126843 |
| 2018-05-12 10:20:00 | The retinal degeneration (rd) mutant mouse, which carries a genetic mutation of PDE6b. | 28812418 |
| 2018-02-17 10:48:00 | These results clearly show that the development of early-onset cataracts requires at least two mutant alleles of Foxe3(rct) and Pde6b(rd1), and another modifier associated with the severity of cataract phenotypes in Foxe3(rct) mice underlies the genetic backgrounds in mice. | 29317205 |
| 2016-06-04 11:16:00 | demonstrated a substantial difference in the speed of retinal degeneration and accompanying loss of visual function between two rd1 lines | 26283863 |
| Type | IDs |
|---|---|
| Synonymous | Pdeb, r, rd, rd-1, rd1, rd10 |
| Gene |
UniProtKB-ID:
PDE6B_MOUSE
UniprotKB:
P23440
UniParc:
UPI000000405A,
UPI000217CB4E
EMBL:
X60133,
AK044364,
CH466529,
X55968
Ensembl:
ENSMUSG00000029491
KO:
mmu:18587
|
| Nucleutide sequences |
EMBL-CDS:
CAA39439.1,
CAA42719.1,
EDL20122.1,
BAC31885.1
Ensembl_TRS:
ENSMUST00000031456
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000031456
RefSeq:
NP_032832.2
|
| Others |
UniRef100:
UniRef100_P23440
UniRef90:
UniRef90_P23440
UniRef50:
UniRef50_P23440
UniGene:
Mm.1372
CCDS:
CCDS19510.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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