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18582 Pde6d

18582

Pde6d

phosphodiesterase 6D, cGMP-specific, rod, delta

protein-coding

Mus musculus

基因描述

Type Description
Definition phosphodiesterase 6D, cGMP-specific, rod, delta

研究结论

Date Results Publications
2018-12-22 11:35:00 It postulates a three-step mechanism regulating ciliary localization of INPP5E, consisting of farnesylation- and PDE6delta-mediated targeting, INPP5E-PDE6delta complex diffusion into the cilium with transfer to the IFT system, and retention inside cilia. 29140789
2016-09-17 12:04:00 the affinity to PDE6delta and the release by Arl2/3 in addition to a retention signal are the determinants for cargo sorting and enrichment at its destination. 27063844
2014-07-26 10:33:00 Knockout of Unc119 partially reversed the transport defect of GRK1 in cone photoreceptors caused by deletion of Pde6d. 24664735
2010-01-21 00:00:00 absence of PrBP/delta in retina impairs transport of prenylated proteins, particularly rhodopsin kinase 1 and cone PDE, to rod and cone outer segments 17496142

名称对应

Type IDs
Synonymous AI841218, PrBP/delta
Gene
UniProtKB-ID: PDE6D_MOUSE, Q3TDQ8_MOUSE
UniprotKB: O55057, Q3TDQ8
UniParc: UPI0000001890
EMBL: AK170067, BC005636, AF039216, AF046000
Ensembl: ENSMUSG00000026239
KO: mmu:18582
Nucleutide sequences
EMBL-CDS: AAC40094.1, AAC25686.1, AAH05636.1, BAE41543.1
Ensembl_TRS: ENSMUST00000027444
Protein sequencees
Ensembl_PRO: ENSMUSP00000027444
RefSeq: NP_032827.1, XP_030108092.1, NP_001347746.1, NP_001347745.1
Others
UniRef100: UniRef100_O55057
UniRef90: UniRef90_O55057
UniRef50: UniRef50_O55057
UniGene: Mm.12925
CCDS: CCDS15121.1

全选

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研究热度

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