| Type | Description |
|---|---|
| Definition | phosphodiesterase 1C |
| Date | Results | Publications |
|---|---|---|
| 2019-03-30 10:53:00 | By whole-mount immunofluorescence on postnatal day 3 mouse cochlea, we show its expression in outer (OHC) and inner (IHC) hair cells cytosol co-localizing with Lamp-1 in lysosomes. Furthermore, we provide evidence that the variant alters the PDE1C hydrolytic activity for both cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). | 29860631 |
| 2019-02-23 12:17:00 | Cardiac Pde1C is a direct transcriptional target of PPARalpha. | 30469494 |
| 2015-06-20 10:51:00 | Ligation injury caused a marked increase in neointimal and medial thickening in PDE1C+/+ mice. Injury-induced neointimal formation was significantly attenuated by PDE1C deficiency (knockout mice) or PDE1 inhibition in vivo. | 25608528 |
| 2010-01-21 00:00:00 | PDE1C is expressed in isolated juxtaglomerular cells, and contributes to calcium's inhibitory modulation of renin release from juxtaglomerular cells. | 19741056 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PDE1C_MOUSE,
Q3USZ6_MOUSE,
A0A5F8MPG4_MOUSE,
E9Q7V6_MOUSE,
Q5D0E7_MOUSE,
A0A0N4SWG4_MOUSE,
Q9D5W0_MOUSE,
Q8CDV2_MOUSE
UniprotKB:
Q64338,
Q3USZ6,
A0A5F8MPG4,
E9Q7V6,
Q5D0E7,
A0A0N4SWG4,
Q9D5W0,
Q8CDV2
UniParc:
UPI00000E88BB,
UPI0003D6E1CC,
UPI00000E91DE,
UPI00005ABF54,
UPI00000EAC49,
UPI0001A42068,
UPI0003D744AA,
UPI0000029A92,
UPI0000001524
EMBL:
L76947,
AC079274,
AK139923,
AK082180,
AC044804,
AC122847,
AC079956,
AK077123,
AK014887,
BC032277,
L76946,
AC079365,
AK030423,
AK029531,
L76944
Ensembl:
ENSMUSG00000004347
KO:
mmu:18575
|
| Nucleutide sequences |
EMBL-CDS:
AAC37702.1,
AAC37701.1,
AAC37703.1,
BAC26956.1,
BAE24184.1,
AAH32277.1,
BAC38431.1,
BAC36626.1,
BAB29604.1,
BAC26499.1
Ensembl_TRS:
ENSMUST00000168944,
ENSMUST00000044505,
ENSMUST00000114327,
ENSMUST00000164752,
ENSMUST00000166102,
ENSMUST00000239143,
ENSMUST00000164037,
ENSMUST00000203372,
ENSMUST00000170774,
ENSMUST00000166890
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129185,
ENSMUSP00000131350,
ENSMUSP00000109966,
ENSMUSP00000128364,
ENSMUSP00000046601,
ENSMUSP00000158960,
ENSMUSP00000130139,
ENSMUSP00000145508,
ENSMUSP00000133170,
ENSMUSP00000131892
RefSeq:
NP_035184.1,
XP_030111081.1,
XP_036021819.1,
XP_017176943.1,
NP_001342404.1,
XP_006505793.1,
XP_006505798.3,
NP_001153424.1,
NP_001153425.1,
NP_001153429.1,
NP_001153428.1,
NP_001153432.1,
NP_001153427.1,
XP_006505797.1,
XP_006505796.1,
NP_001020739.1
|
| Others |
UniRef100:
UniRef100_A0A5F8MPG4,
UniRef100_Q9D5W0,
UniRef100_E9Q7V6,
UniRef100_Q8CDV2,
UniRef100_A0A0N4SWG4,
UniRef100_Q64338,
UniRef100_Q3USZ6,
UniRef100_Q5D0E7
UniRef90:
UniRef90_Q64338-1,
UniRef90_A0A286ZIV6,
UniRef90_F1LMX4,
UniRef90_Q64338
UniRef50:
UniRef50_F1LMX4,
UniRef50_Q64338,
UniRef50_Q64338-1
UniGene:
Mm.5145
CCDS:
CCDS51785.1,
CCDS51784.1,
CCDS20170.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员