| Type | Description |
|---|---|
| Definition | dishevelled segment polarity protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:53:00 | Dishevelled 1-Regulated Superpotent Cancer Stem Cells Mediate Wnt Heterogeneity and Tumor Progression in Hepatocellular Carcinoma. | 32160521 |
| 2020-08-15 19:03:00 | Oxidative stress upregulates Wnt signaling in human retinal microvascular endothelial cells through activation of disheveled. | 30963607 |
| 2019-08-24 12:18:00 | These results provide new insight into the mechanisms underlying hyperactivation of the Wnt/beta-catenin pathway in hepatocellular carcinoma, as well the oncogenic ability of TFAP4 to enhance the tumor-forming ability of hepatocellular carcinoma cells via its binding to the promoters of DVL1 (dishevelled segment polarity protein 1) and LEF1 (lymphoid enhancer binding factor 1). | 30026867 |
| 2019-06-08 11:08:00 | Dishevelled 1, a pivotal positive regulator of the Wnt signalling pathway, mediates 5-fluorouracil resistance in HepG2 cells | 29583038 |
| 2019-06-01 10:51:00 | Data show that Dishevelled 1 (DVL1) was a direct target of miR-1247-5p. | 30249392 |
| Type | IDs |
|---|---|
| Synonymous | DRS2, DVL, DVL1L1, DVL1P1 |
| Gene |
UniProtKB-ID:
DVL1_HUMAN
UniprotKB:
O14640
UniParc:
UPI00001AF922,
UPI000013D455
EMBL:
AL139287,
AF006011
Ensembl:
ENSG00000107404
KO:
hsa:1855
|
| Nucleutide sequences |
EMBL-CDS:
AAB65242.1
Ensembl_TRS:
ENST00000378888,
ENST00000378891
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000368169,
ENSP00000368166
RefSeq:
NP_001317240.1,
XP_005244790.1,
NP_004412.2,
XP_005244789.1
|
| Others |
UniRef100:
UniRef100_O14640
UniRef90:
UniRef90_P51141
UniRef50:
UniRef50_P51141
UniGene:
Hs.731450
CCDS:
CCDS81252.1,
CCDS22.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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