| Type | Description |
|---|---|
| Definition | proprotein convertase subtilisin/kexin type 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:03:00 | Translation of insulin granule proteins are regulated by PDI and PABP. | 32248978 |
| 2018-06-16 10:19:00 | Study reveals a significant reduction of tachykinin and opioid neuropeptides level in proprotein convertase 1 and proprotein convertase 2 mutant mouse spinal cords. | 28476408 |
| 2017-07-29 11:49:00 | Study reports that PC2 null mice had increased number of mu opioid receptors in different brain areas. These mice also exhibited enhanced morphine-induced antinociception but reduced tolerance to and dependence on morphine. | 27208618 |
| 2016-08-27 12:03:00 | PC1 and PC2 are involved in the C-terminal processing of protachykinin peptides and suggest a major role in the maturation of the protachykinin-1 protein | 26373413 |
| 2016-05-28 12:32:00 | activation of the hypothalamic GPR40/FFA1 signaling pathway may regulate beta-endorphin release via PC2, and regulate the endogenous pain control system | 26071852 |
| Type | IDs |
|---|---|
| Synonymous | 6330411F23Rik, AI839700, Nec-2, Nec2, PC2, Phpp-2, SPC2 |
| Gene |
UniProtKB-ID:
NEC2_MOUSE,
Q547J8_MOUSE
UniprotKB:
P21661,
Q547J8
UniParc:
UPI0000001101
EMBL:
BC057348,
M55669,
AF483513,
AK158598,
AY902322,
BC052013,
AF483512
Ensembl:
ENSMUSG00000027419
KO:
mmu:18549
|
| Nucleutide sequences |
EMBL-CDS:
AAA39376.1,
AAH52013.2,
AAH57348.1,
AAL90787.1,
BAE34574.1,
AAL90786.1,
AAX90607.1
Ensembl_TRS:
ENSMUST00000028905
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028905
RefSeq:
NP_032818.1
|
| Others |
UniRef100:
UniRef100_P21661
UniRef90:
UniRef90_P16519
UniRef50:
UniRef50_P16519
UniGene:
Mm.294493,
Mm.447466
CCDS:
CCDS16810.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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