例如:"NBL1", "4681", "drought"
收藏
18548 Pcsk1

18548

Pcsk1

proprotein convertase subtilisin/kexin type 1

protein-coding

Mus musculus

基因描述

Type Description
Definition proprotein convertase subtilisin/kexin type 1

研究结论

Date Results Publications
2020-12-12 13:24:00 A novel mutation in the mouse Pcsk1 gene showing obesity and diabetes. 31974728
2020-12-05 13:03:00 Translation of insulin granule proteins are regulated by PDI and PABP. 32248978
2019-09-14 13:19:00 pancreatic cancer-derived exosomes (Exo-Mia) suppress the synthesis of GIP and GLP-1 from STC-1cells in vitro by down-regulating the PCSK1/3 29800682
2018-06-16 10:19:00 Study reveals a significant reduction of tachykinin and opioid neuropeptides level in proprotein convertase 1 and proprotein convertase 2 mutant mouse spinal cords. 28476408
2018-03-17 11:57:00 Oxygen and glucose deprivation or middle cerebral artery occlusion stress caused substantial cell death in a dose-dependent manner. With the increasing OGD dose, proPC1 and PC1 proteins gradually increased. In vivo the proPC1 and PC1 expressions presented with a peak at 4-h and then decreased at 24-h reperfusion. The results suggest that the increasing PC1 expression promoted the transformation of proCgA into CgA or small 29198128

名称对应

Type IDs
Synonymous Nec-1, Nec1, PC1, PC3, Phpp-1, SPC3
Gene
UniProtKB-ID: NEC1_MOUSE, Q32MU0_MOUSE
UniprotKB: P63239, Q32MU0
UniParc: UPI0000021C5C
EMBL: BC108982, X57088, M69196, M55668, BC108983, M58589
Ensembl: ENSMUSG00000021587
KO: mmu:18548
Nucleutide sequences
EMBL-CDS: AAA39732.1, AAA39375.1, AAA39894.1, CAA40368.1, AAI08984.1, AAI08983.1
Ensembl_TRS: ENSMUST00000022075
Protein sequencees
Ensembl_PRO: ENSMUSP00000022075
RefSeq: XP_006517216.1, NP_038656.1, XP_006517217.1, XP_006517218.1
Others
UniRef100: UniRef100_P63239
UniRef90: UniRef90_P28840
UniRef50: UniRef50_P28840
UniGene: Mm.1333
CCDS: CCDS26649.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员