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18521 Pcbp2

18521

Pcbp2

poly(rC) binding protein 2

protein-coding

Mus musculus

基因描述

Type Description
Definition poly(rC) binding protein 2

研究结论

Date Results Publications
2019-06-22 11:14:00 Embryos lacking the KH domain poly(C) binding protein, Pcbp2, are selectively deficient in the definitive erythroid lineage. Compared to wild-type controls, transcript splicing analysis of the Pcbp2(-/-) embryonic liver reveals accentuated exclusion of an exon (exon 6) that encodes a highly conserved transcriptional control segment of the hematopoietic master regulator, Runx1. 29866654
2019-01-19 11:04:00 These findings suggest that Hr mRNA expression is regulated at the post-transcriptional level via IRES-mediated translation control through interaction with PCPB2, but not in MUHH. 29422543
2017-05-13 13:42:00 Study determined that PCBP2 specifically associates with components of this kinase cascade and regulates the activities of its downstream transcriptional coactivators. 27215387
2016-11-12 11:52:00 data suggest that PCBP2 regulates p73 expression via mRNA stability and p73-dependent biological function in production and cellular senescence. 26907686
2016-10-22 12:17:00 PCBP2 overexpression rescues the Meis1 effects of Akt-mTOR pathway and hypertrophy of cardiomyocytes. 26597775

名称对应

Type IDs
Synonymous AW412548, Hnrpx, alphaCP-2
Gene
UniProtKB-ID: PCBP2_MOUSE, Q3TT81_MOUSE, A0A2R8VHP9_MOUSE, B2M1R7_MOUSE
UniprotKB: Q61990, Q3TT81, A0A2R8VHP9, B2M1R7
UniParc: UPI0000000C25, UPI000002B0AD, UPI0000473FA6, UPI00001867C9, UPI0000024DE2, UPI0000520BBC
EMBL: AF236845, AF236844, X97982, L19661, EU604548, AF236843, AK161527, AC137156, AF236842, X75947
Ensembl: ENSMUSG00000056851
KO: mmu:18521
Nucleutide sequences
EMBL-CDS: AAK14059.1, CAA53546.1, CAA66619.1, AAA03705.1, BAE36444.1, ACC69194.1
Ensembl_TRS: ENSMUST00000078404, ENSMUST00000229618, ENSMUST00000077037, ENSMUST00000229854, ENSMUST00000108838, ENSMUST00000229918, ENSMUST00000229802, ENSMUST00000230114
Protein sequencees
Ensembl_PRO: ENSMUSP00000155038, ENSMUSP00000076294, ENSMUSP00000155430, ENSMUSP00000077509, ENSMUSP00000104466, ENSMUSP00000155292, ENSMUSP00000155072, ENSMUSP00000155789
RefSeq: XP_030104246.1, XP_030104265.1, XP_030104260.1, XP_006520647.1, XP_006520645.1, NP_035172.2, NP_001167544.1, XP_011243808.1, XP_011243804.1, XP_011243798.1, XP_011243799.1, XP_017171990.1, NP_001096635.1, XP_011243797.1, NP_001096636.1, XP_011243807.1, XP_030104248.1, XP_011243800.1, XP_030104256.1, XP_030104251.1, XP_030104262.1, XP_011243805.1, NP_001361700.1, XP_030104264.1, XP_030104261.1, XP_030104250.1, XP_030104247.1, XP_011243811.1, XP_017171987.1, XP_011243802.1, XP_011243810.1, XP_030104259.1, XP_030104263.1, XP_006520649.1, XP_011243806.1, XP_030104254.1, XP_030104249.1, XP_006520648.1, XP_030104266.1, XP_030104258.1, XP_006520646.1, XP_011243801.1, XP_011243809.1, XP_030104253.1, XP_011243803.1, XP_030104252.1, XP_017171988.1, XP_017171989.1, XP_030104255.1, XP_017171986.1
Others
UniRef100: UniRef100_A0A2R8VHP9, UniRef100_Q3TT81, UniRef100_B2M1R7, UniRef100_Q61990
UniRef90: UniRef90_A0A455BEB1, UniRef90_Q15366
UniRef50: UniRef50_Q15366, UniRef50_P57721-2
UniGene: Mm.236513
CCDS: CCDS49742.1, CCDS27884.1, CCDS49741.1

全选

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