Type | Description |
---|---|
Definition | paired box 8 |
Date | Results | Publications |
---|---|---|
2020-02-01 10:44:00 | PAX8 is a unifying protein driving metastasis in ovarian tumors that could be developed as an effective drug target to treat High Grade serous ovarian cancer derived from both the Ovarian surface epithelium and Fallopian tube epithelium. | 31296958 |
2018-05-19 12:20:00 | Results show that in both 3- and 8-week-old offspring of the maternal group highly treated with E2, Pax8 was significantly up-regulated in thyroid glands, accompanied by the abnormal CpG island methylation status in the promoter region. | 27827435 |
2018-02-03 10:47:00 | Demonstrate the stepwise emergence of hitherto undescribed, differently Pax2/Pax8- coded anterior and posterior subdomains in the posterior placodal area of mice. | 28160066 |
2017-12-30 12:34:00 | PAX8 has a cell specific role in governing proliferation and migration in nontransformed ovarian surface epithelium cells compared to the oviductal cells, but its reduction in serous cancer cell lines provides a common mechanism for reducing cell survival. | 27129161 |
2017-01-14 10:12:00 | These results suggest that Pax8 maybe the downstream molecule of ALK3, it mediates the murine heart development via cellular senescence, which may serve as a mechanism that compensates for the cell loss via apoptosis in heart development. | 26781745 |
Type | IDs |
---|---|
Synonymous | Pax-8 |
Gene |
UniProtKB-ID:
PAX8_MOUSE
UniprotKB:
Q00288
UniParc:
UPI000000199B
EMBL:
AL732528,
X99592,
X99594,
X99597,
X99593,
X99598,
X57487,
X99595,
CH466542,
X99596,
BC020526
Ensembl:
ENSMUSG00000026976
KO:
mmu:18510
|
Nucleutide sequences |
EMBL-CDS:
AAH20526.1,
CAA67904.1,
CAA40725.1,
EDL08172.1
Ensembl_TRS:
ENSMUST00000028355
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028355
RefSeq:
NP_035170.1
|
Others |
UniRef100:
UniRef100_Q00288
UniRef90:
UniRef90_Q00288
UniRef50:
UniRef50_Q00288
UniGene:
Mm.2533
CCDS:
CCDS15738.1
|
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