| Type | Description |
|---|---|
| Definition | paired box 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:16:00 | Pax5 Negatively Regulates Osteoclastogenesis through Downregulation of Blimp1. | 33672551 |
| 2021-03-13 13:22:00 | Inhibition of inflammatory signaling in Pax5 mutant cells mitigates B-cell leukemogenesis. | 33154497 |
| 2020-09-05 13:59:00 | Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion. | 32612238 |
| 2020-01-11 10:45:00 | Gene expression analysis of mouse models and primary human leukemia suggested that reduced function of PAX5 increased the ability of an oncogenic form of IKZF1 or ETV6-AML to modulate gene expression. Data reveals that PAX5 belong to a regulatory network frequently targeted by multiple mutations in B-lineage acute lymphoblastic leukemia shedding light on the molecular interplay in leukemia cells. | 31381561 |
| 2019-06-15 12:41:00 | Loss of Pax5 drives metabolic reprogramming, which together with Sca1-restricted BCR-ABL expression enables leukemic transformation. | 29490943 |
| Type | IDs |
|---|---|
| Synonymous | BSAP, EBB-1, KLP, Pax-5 |
| Gene |
UniProtKB-ID:
PAX5_MOUSE
UniprotKB:
Q02650
UniParc:
UPI0000029720
EMBL:
M97013
Ensembl:
ENSMUSG00000014030
KO:
mmu:18507
|
| Nucleutide sequences |
EMBL-CDS:
AAA37325.1
Ensembl_TRS:
ENSMUST00000014174
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000014174
RefSeq:
NP_032808.1
|
| Others |
UniRef100:
UniRef100_Q02650
UniRef90:
UniRef90_Q02650
UniRef50:
UniRef50_Q02548-11
UniGene:
Mm.439659
CCDS:
CCDS18125.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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