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18506 Pax4

18506

Pax4

paired box 4

protein-coding

Mus musculus

基因描述

Type Description
Definition paired box 4

研究结论

Date Results Publications
2018-04-14 10:33:00 Down-regulation of PAX4 or its target gene encoding the p97/VCP ATPase reduced myofibril disassembly. 28096335
2017-12-09 11:44:00 Ectopic expression of Pax4 in pancreatic delta cells results in beta-like cell neogenesis. 29025873
2016-12-17 11:54:00 The coordinated regulation of distinct cellular pathways particularly related to ER homeostasis by PAX4 not achieved by the mutant variant PAX4R129W alleviates beta cell degeneration and protects against diabetes mellitus. 26813254
2016-09-17 10:13:00 This work establishes the existence of a bona fide PAX4-enriched cell subpopulation nested within pancreatic islets that can expand in periods of increased functional demands, and exhibit improved viability in response to pathophysiological situations. 26503027
2016-05-21 12:43:00 Pax4 expression is not sufficient to transduce pancreatic alpha cells into beta cells. Overexpression of Pax4 in alpha cells may not increase functional beta cell number in diabetic patients 26183751

名称对应

Type IDs
Synonymous Pax-4
Gene
UniProtKB-ID: PAX4_MOUSE, A2RRY5_MOUSE, B7ZNC8_MOUSE
UniprotKB: P32115, A2RRY5, B7ZNC8
UniParc: UPI000189A8B6, UPI000002B099, UPI0000029C95, UPI000002B098
EMBL: AF104231, AC068608, BC145168, AF145233, BC131908, BC145169, Y09584, AB008912, AF031150, BC131906, AB010558, AF142321, AB010557
Ensembl: ENSMUSG00000029706
KO: mmu:18506
Nucleutide sequences
EMBL-CDS: AAF03530.1, BAA24517.1, AAI45169.1, AAF14073.1, AAF03533.1, CAA70772.1, BAA24516.1, AAC40046.1, BAA24505.1, AAI31909.1, AAI31907.1, AAI45170.1
Ensembl_TRS: ENSMUST00000031718, ENSMUST00000164519, ENSMUST00000171089
Protein sequencees
Ensembl_PRO: ENSMUSP00000031718, ENSMUSP00000131301, ENSMUSP00000126000
RefSeq: NP_001153398.1, NP_001153397.1, NP_035168.1
Others
UniRef100: UniRef100_P32115, UniRef100_B7ZNC8
UniRef90: UniRef90_P32115
UniRef50: UniRef50_P32115
UniGene: Mm.8026
CCDS: CCDS51732.1, CCDS39447.1

全选

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