| Type | Description |
|---|---|
| Definition | dual specificity phosphatase 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:08:00 | Dual-specificity phosphatase 6 plays a critical role in the maintenance of a cancer stem-like cell phenotype in human endometrial cancer. | 32159851 |
| 2021-03-13 13:17:00 | TRIM59, amplified in ovarian cancer, promotes tumorigenesis through the MKP3/ERK pathway. | 31951023 |
| 2020-07-04 11:47:00 | TRIM11 might suppress the translation of DUSP6 via improving its ubiquitination. Additionally, TRIM11 silencing in osteosarcoma (OS) cells significantly reduced its tumorigenicity in vivo. | 31950060 |
| 2019-12-07 11:50:00 | DUSP6 protein expression was predominantly nuclear in breast CTCs and the brain metastases but not pleura or lung metastases of TNBC patients. Therefore, nuclear DUSP6 may play a role in the association with cancer spreading in TNBC patients, including brain metastasis. | 31238530 |
| 2019-08-17 10:53:00 | DUSP6 is a tumor suppressor in Non-small cell lung cancer. | 31027181 |
| Type | IDs |
|---|---|
| Synonymous | HH19, MKP3, PYST1 |
| Gene |
UniProtKB-ID:
DUS6_HUMAN,
A0A024RBC1_HUMAN,
Q53GP9_HUMAN
UniprotKB:
Q16828,
A0A024RBC1,
Q53GP9
UniParc:
UPI000002A866,
UPI000013ED2F,
UPI000013DBD3
EMBL:
AB013382,
BC003143,
BC037236,
AB013601,
AB013602,
X93920,
BC005047,
CH471054,
BT006895,
AK222882,
BC003562
Ensembl:
ENSG00000139318
KO:
hsa:1848
|
| Nucleutide sequences |
EMBL-CDS:
AAH03562.1,
AAP35541.1,
AAH37236.1,
CAA63813.1,
BAA31968.1,
AAH03143.1,
AAH05047.1,
BAA34369.1,
BAA31969.1,
EAW97423.1,
EAW97422.1,
BAD96602.1
Gene_ORFName:
hCG_26604
Ensembl_TRS:
ENST00000279488,
ENST00000308385
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000307835,
ENSP00000279488
RefSeq:
NP_001937.2,
NP_073143.2
|
| Others |
UniRef100:
UniRef100_Q53GP9,
UniRef100_Q16828
UniRef90:
UniRef90_A0A1W2P715,
UniRef90_Q16828
UniRef50:
UniRef50_A0A1W2P715,
UniRef50_Q16828
UniGene:
Hs.298654,
Hs.718640
CCDS:
CCDS9034.1,
CCDS9033.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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