例如:"NBL1", "4681", "drought"
收藏
1848 DUSP6

1848

DUSP6

dual specificity phosphatase 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition dual specificity phosphatase 6

研究结论

Date Results Publications
2021-04-13 10:08:00 Dual-specificity phosphatase 6 plays a critical role in the maintenance of a cancer stem-like cell phenotype in human endometrial cancer. 32159851
2021-03-13 13:17:00 TRIM59, amplified in ovarian cancer, promotes tumorigenesis through the MKP3/ERK pathway. 31951023
2020-07-04 11:47:00 TRIM11 might suppress the translation of DUSP6 via improving its ubiquitination. Additionally, TRIM11 silencing in osteosarcoma (OS) cells significantly reduced its tumorigenicity in vivo. 31950060
2019-12-07 11:50:00 DUSP6 protein expression was predominantly nuclear in breast CTCs and the brain metastases but not pleura or lung metastases of TNBC patients. Therefore, nuclear DUSP6 may play a role in the association with cancer spreading in TNBC patients, including brain metastasis. 31238530
2019-08-17 10:53:00 DUSP6 is a tumor suppressor in Non-small cell lung cancer. 31027181

名称对应

Type IDs
Synonymous HH19, MKP3, PYST1
Gene
UniProtKB-ID: DUS6_HUMAN, A0A024RBC1_HUMAN, Q53GP9_HUMAN
UniprotKB: Q16828, A0A024RBC1, Q53GP9
UniParc: UPI000002A866, UPI000013ED2F, UPI000013DBD3
EMBL: AB013382, BC003143, BC037236, AB013601, AB013602, X93920, BC005047, CH471054, BT006895, AK222882, BC003562
Ensembl: ENSG00000139318
KO: hsa:1848
Nucleutide sequences
EMBL-CDS: AAH03562.1, AAP35541.1, AAH37236.1, CAA63813.1, BAA31968.1, AAH03143.1, AAH05047.1, BAA34369.1, BAA31969.1, EAW97423.1, EAW97422.1, BAD96602.1
Gene_ORFName: hCG_26604
Ensembl_TRS: ENST00000279488, ENST00000308385
Protein sequencees
Ensembl_PRO: ENSP00000307835, ENSP00000279488
RefSeq: NP_001937.2, NP_073143.2
Others
UniRef100: UniRef100_Q53GP9, UniRef100_Q16828
UniRef90: UniRef90_A0A1W2P715, UniRef90_Q16828
UniRef50: UniRef50_A0A1W2P715, UniRef50_Q16828
UniGene: Hs.298654, Hs.718640
CCDS: CCDS9034.1, CCDS9033.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员