| Type | Description |
|---|---|
| Definition | platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:07:00 | Emergence of non-canonical parvalbumin-containing interneurons in hippocampus of a murine model of type I lissencephaly. | 33150866 |
| 2019-06-15 12:20:00 | This study demonstrated that LIS1 supports synaptic function and plasticity of mature CA1 neurons. | 29150182 |
| 2019-01-12 10:19:00 | genetic deletion of Lis1 in the mouse liver increases lipid accumulation and inflammation in this organ. Further analysis revealed that loss of Lis1 triggers endoplasmic reticulum (ER) stress and reduces triglyceride secretion. | 29475944 |
| 2019-01-05 12:01:00 | Lis1 loss in the midbrain/hindbrain causes a severe phenotype. Brainstem regions known to house cardiorespiratory centers showed signs of axonal dysfunction in KO animals. Transport defects, neurofilament alterations, and varicosities were observed in axons in cultured dorsal root ganglia neurons from KO animals. | 29404402 |
| 2018-06-30 10:21:00 | This study examined the effect of Pafah1b1 overexpression on radial migration of cerebral cortical neurons and found that enhanced expression of Pafah1b1 caused over-migration of neurons into the marginal zone, and Pafah1b1-overexpressing neurons that entered the marginal zone were disoriented. | 28836069 |
| Type | IDs |
|---|---|
| Synonymous | LIS-1, Lis1, MMS10-U, Mdsh, Ms10u, Pafaha |
| Gene |
UniProtKB-ID:
LIS1_MOUSE,
Q5SW18_MOUSE
UniprotKB:
P63005,
Q5SW18
UniParc:
UPI0000001952,
UPI000016CAD6
EMBL:
AK164008,
AK147507,
U95120,
AK144908,
AK168960,
L25109,
AK147207,
AK147237,
BC014831,
U95116,
U95119,
AK147533,
AK168929,
AY189217,
AY189218,
BC026141
Ensembl:
ENSMUSG00000020745
KO:
mmu:18472
|
| Nucleutide sequences |
EMBL-CDS:
AAH14831.1,
AAH26141.1,
AAC04610.1,
AAO41716.1,
AAC63099.1,
AAD23059.1,
AAC63098.1,
AAO41717.1,
BAE27787.1,
BAE40766.1,
BAE27764.1,
BAE26129.1,
BAE37586.1,
BAE40742.1,
BAE27977.1,
BAE27961.1
Ensembl_TRS:
ENSMUST00000102520,
ENSMUST00000021091
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099578,
ENSMUSP00000021091
RefSeq:
NP_038653.1
|
| Others |
UniRef100:
UniRef100_P63005
UniRef90:
UniRef90_P63005
UniRef50:
UniRef50_P63005
UniGene:
Mm.397111
CCDS:
CCDS25035.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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