| Type | Description |
|---|---|
| Definition | dual specificity phosphatase 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:24:00 | DUSP4 is involved in the enhanced proliferation and survival of DUSP4-overexpressing cancer cells. | 32505357 |
| 2020-10-24 13:59:00 | Dual-specificity protein phosphatase DUSP4 regulates response to MEK inhibition in BRAF wild-type melanoma. | 31839677 |
| 2020-09-12 16:02:00 | miR-137 alleviates doxorubicin resistance in breast cancer through inhibition of epithelial-mesenchymal transition by targeting DUSP4. | 31801953 |
| 2020-07-04 12:18:00 | show that a high GFAP-delta/alpha ratio induces the expression of the dual-specificity phosphatase 4 (DUSP4) in focal adhesions. By focusing on pathways up- and downstream of DUSP4 that are involved in the cell-extracellular matrix interaction, we show that a high GFAP-delta/alpha ratio equips glioma cells to better invade the brain | 31480854 |
| 2020-05-30 10:55:00 | It findings identify the CREMalpha/DUSP4 axis as a promising candidate in the search for biomarkers and therapeutic targets in systemic lupus erythematosus. | 31653682 |
| Type | IDs |
|---|---|
| Synonymous | HVH2, MKP-2, MKP2, TYP |
| Gene |
UniProtKB-ID:
DUS4_HUMAN
UniprotKB:
Q13115
UniParc:
UPI0000071D66,
UPI00000362F4
EMBL:
AL137704,
CH471080,
BC014565,
BC002671,
AK314820,
AC084262,
U48807,
U21108
Ensembl:
ENSG00000120875
KO:
hsa:1846
|
| Nucleutide sequences |
EMBL-CDS:
AAH14565.1,
EAW63483.1,
AAA85119.1,
EAW63484.1,
EAW63482.1,
BAG37342.1,
EAW63481.1,
AAC50452.1,
AAH02671.1
Ensembl_TRS:
ENST00000240100,
ENST00000240101
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000240100,
ENSP00000240101
RefSeq:
NP_001385.1,
XP_011542730.1,
NP_476499.1
|
| Others |
UniRef100:
UniRef100_Q13115
UniRef90:
UniRef90_Q13115
UniRef50:
UniRef50_Q13115
UniGene:
Hs.417962
CCDS:
CCDS6073.1,
CCDS6072.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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