| Type | Description |
|---|---|
| Definition | dual specificity phosphatase 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:24:00 | Regulation of signal transducer and activator of transcription 3 activation by dual-specificity phosphatase 3. | 32475380 |
| 2021-01-23 12:58:00 | Allosteric Impact of the Variable Insert Loop in Vaccinia H1-Related (VHR) Phosphatase. | 32348128 |
| 2019-01-12 10:03:00 | Study demonstrated that miR-1915-3p might promote the proliferation and metastasis of breast cancer by repression of DUSP3 and serum miR-1915-3p and miR-455-3p could serve as diagnostic and predictive biomarkers for breast cancer. | 30048472 |
| 2018-06-09 10:12:00 | Nuclear HSP70 leads to enhancement of vaccinia H1-related phosphatase (VHR) activity via protein-protein interaction rather than its molecular chaperone activity, thereby suppressing excessive ERK activation. Downregulation of either VRK3 or HSP70 rendered cells vulnerable to glutamate-induced apoptosis. | 27941812 |
| 2017-12-09 13:36:00 | Data indicated that regulating non-receptor tyrosine kinase FAK and cell migration is a newly revealed function of VHR/DUSP3. | 28759036 |
| Type | IDs |
|---|---|
| Synonymous | VHR |
| Gene |
UniProtKB-ID:
DUS3_HUMAN
UniprotKB:
P51452
UniParc:
UPI000007423F,
UPI000012995E
EMBL:
BC002682,
CH471178,
AC003098,
BC035701,
L05147,
BT019522,
AC055813
Ensembl:
ENSG00000108861
KO:
hsa:1845
|
| Nucleutide sequences |
EMBL-CDS:
AAA35777.1,
AAH02682.1,
AAV38329.1,
EAW51668.1,
EAW51667.1,
AAH35701.1
Ensembl_TRS:
ENST00000226004
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000226004
RefSeq:
NP_004081.1
|
| Others |
UniRef100:
UniRef100_P51452
UniRef90:
UniRef90_P51452
UniRef50:
UniRef50_P51452
UniGene:
Hs.181046
CCDS:
CCDS11469.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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