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18441 P2ry1

18441

P2ry1

purinergic receptor P2Y, G-protein coupled 1

protein-coding

Mus musculus

基因描述

Type Description
Definition purinergic receptor P2Y, G-protein coupled 1

研究结论

Date Results Publications
2020-06-20 11:48:00 Study demonstrates that the metabotropic P2Y1 receptor mediates either proconvulsive or anticonvulsive responses, dependent on the time point of activation in relation to the induction of status epilepticus. 31048325
2020-06-20 10:06:00 microglial P2Y1R mediate neuroprotective effects against ischemic stress and oxygen-glucose deprivation insult. 30334687
2019-12-21 12:27:00 Energy depletion and ADP elevation in sensory afferents, due to mitochondrial respiratory chain complex IV deficiency, appear sufficient to induce pain hypersensitivity, by ADP activation of P2Y1 receptors. 30689196
2019-10-05 12:03:00 We analyzed the presence and clearance of TAM and its metabolites (N-desmethyl-tamoxifen, 4-hydroxytamoxifen and endoxifen) in brain and serum of mice by liquid chromatographic-high resolution-tandem mass spectrometry (LC-HR-MS/MS) and assessed optimal injection protocols by quantitative RT-PCR of several floxed target genes (p2ry1, gria1, gabbr1 and Rosa26-tdTomato locus). 29651133
2019-08-10 11:47:00 Here, the authors provide genetic evidence that activity-induced calcium accumulation in neonatal terminal/perisynaptic Schwann cells is mediated exclusively by one subtype of metabotropic purinergic receptor, P2ry1. 29384476

名称对应

Type IDs
Synonymous P2Y1
Gene
UniProtKB-ID: P2RY1_MOUSE, Q8BMJ5_MOUSE, Q544J5_MOUSE
UniprotKB: P49650, Q8BMJ5, Q544J5
UniParc: UPI0000003FD5, UPI00000EB313
EMBL: U22829, BC138634, BC138635, AK033660, AK036611, AJ245636, AK030759
Ensembl: ENSMUSG00000027765
KO: mmu:18441
Nucleutide sequences
EMBL-CDS: CAB57317.1, AAA91302.1, BAC27125.1, BAC28413.1, AAI38636.1, AAI38635.1, BAC29506.1
Ensembl_TRS: ENSMUST00000193201, ENSMUST00000029331, ENSMUST00000193943
Protein sequencees
Ensembl_PRO: ENSMUSP00000142006, ENSMUSP00000141371, ENSMUSP00000029331
RefSeq: NP_001268945.1, NP_032798.1
Others
UniRef100: UniRef100_Q8BMJ5, UniRef100_P49650
UniRef90: UniRef90_P49651
UniRef50: UniRef50_P49651
UniGene: Mm.281452
CCDS: CCDS17377.1

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