| Type | Description |
|---|---|
| Definition | ornithine transcarbamylase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:29:00 | An Exon-Specific Small Nuclear U1 RNA (ExSpeU1) Improves Hepatic OTC Expression in a Splicing-Defective spf/ash Mouse Model of Ornithine Transcarbamylase Deficiency. | 33228018 |
| 2016-08-06 10:48:00 | Gene correction in adult OTC-deficient mice was lower and accompanied by larger deletions that ablated residual expression from the endogenous OTC gene, leading to diminished protein tolerance and lethal hyperammonemia on a chow diet | 26829317 |
| 2016-03-26 10:49:00 | The corresponding OTC tissue enzyme activities were between 3-6% of normal control in mouse and human liver. The use of the cryptic splice sites was reproduced in minigenes carrying murine or human mutant sequences | 25853564 |
| 2010-05-03 11:47:00 | Serum OCT seemed to reflect tumor necrosis factor-alpha-mediated hepatic damage in diabetic obese mice and could be useful in the application for non-alcoholic fatty liver disease with features of metabolic syndrome, such as obesity and diabetes. | 19793175 |
| 2010-01-21 00:00:00 | Phenotypic correction of OTC deficiency using low-dose helper-dependent adenoviral vectors is reported. | 18563850 |
| Type | IDs |
|---|---|
| Synonymous | AI265390, Sf, spf |
| Gene |
UniProtKB-ID:
OTC_MOUSE,
Q543H3_MOUSE,
Q8R1A8_MOUSE
UniprotKB:
P11725,
Q543H3,
Q8R1A8
UniParc:
UPI00000040BD,
UPI00000E7123
EMBL:
AK050930,
X07098,
X07096,
M17030,
X07099,
X07093,
BC024893,
X07094,
X07097,
M12716,
X07100,
AL671042,
X07092,
X07095
Ensembl:
ENSMUSG00000031173
KO:
mmu:18416
|
| Nucleutide sequences |
EMBL-CDS:
AAA39865.1,
AAA39864.1,
CAA30121.1,
BAC34465.1,
AAH24893.1
Ensembl_TRS:
ENSMUST00000049910,
ENSMUST00000115528
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000056152,
ENSMUSP00000111190
RefSeq:
NP_032795.1,
XP_011245751.1
|
| Others |
UniRef100:
UniRef100_P11725,
UniRef100_Q8R1A8
UniRef90:
UniRef90_Q8R1A8,
UniRef90_P00481
UniRef50:
UniRef50_P00481
UniGene:
Mm.2611
CCDS:
CCDS30015.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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