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1841 DTYMK

1841

DTYMK

deoxythymidylate kinase

protein-coding

Homo sapiens

基因描述

Type Description
Definition deoxythymidylate kinase

研究结论

Date Results Publications
2020-01-04 11:31:00 DTYMK is a novel gene for mitochondrial DNA depletion syndrome 31271740
2019-08-10 11:38:00 these findings suggest that Tip60-ATM signaling has a functional contribution to the recruitment of TMPK to DNA damage sites, thereby increasing local dTTP synthesis for DNA repair. 30199284
2019-04-20 11:39:00 The RAMD simulations on product-bound structures of both ttTMPK and hTMPK, revealed that while several exit patterns of the products are permissible, the sequential exit mode is the most preferred pattern for both ttTMPK and hTMPK enzymes. Additionally, the product release from the hTMPK was found to be faster and more directional as compared to ttTMPK 30447376
2010-01-21 00:00:00 Lentiviral delivery of small hairpin RNA targeting TMPK in combination with a low dose of doxorubicin as a new approach to kill colon cancer cells regardless of p53 status. 18413751

名称对应

Type IDs
Synonymous CDC8, PP3731, TMPK, TYMK
Gene
UniProtKB-ID: KTHY_HUMAN, Q53F55_HUMAN, Q6FGU2_HUMAN
UniprotKB: P23919, Q53F55, Q6FGU2
UniParc: UPI00004115F3, UPI000050A9B7, UPI000013EA9F
EMBL: BC147006, AK223434, AC133528, CR542015, L16991, BC147010, BC171902, CH471063, BC001827, X54729, CR541986
Ensembl: ENSG00000168393
KO: hsa:1841
Nucleutide sequences
EMBL-CDS: AAA21719.1, CAA38528.1, CAG46783.1, AAH01827.1, AAI71902.1, BAD97154.1, AAI47007.1, AAY14920.1, CAG46812.1, AAI47011.1, EAW71284.1
Gene_ORFName: hCG_93868
Ensembl_TRS: ENST00000305784
Protein sequencees
Ensembl_PRO: ENSP00000304802
RefSeq: NP_001307831.1, NP_001307834.1, NP_001307832.1, NP_036277.2, NP_001158503.1, NP_001307833.1
Others
UniRef100: UniRef100_Q53F55, UniRef100_P23919
UniRef90: UniRef90_G3QFV9, UniRef90_P23919
UniRef50: UniRef50_P23919, UniRef50_G3QFV9
UniGene: Hs.471873
CCDS: CCDS2552.1

全选

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