| Type | Description |
|---|---|
| Definition | dentin sialophosphoprotein |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 11:46:00 | Significantly high expression levels of MMP20 and DSPP were observed in the malignant breast, colon, prostate, thyroid, and cervical neoplasms compared with their benign and normal counterparts. Furthermore, MMP20 levels increased with advanced stages of colon and thyroid cancers. DSPP expression increased significantly with tumor stage in all cancers examined. | 30932369 |
| 2020-04-18 12:38:00 | Novel frameshift mutations in DSPP cause dentin dysplasia type II | 31454439 |
| 2019-06-29 10:20:00 | A heterozygous c.50C to T (p.P17L) mutation was identified in exon 2 of the DSPP gene in hereditary dentinogenesis imperfecta | 30098245 |
| 2018-12-22 12:00:00 | Taken together, these findings indicate that knockdown of DSPP inhibits glioma cells migration and invasion, suggesting that targeting DSPP might be a potentially effective therapeutic strategy for treating glioma. | 30309696 |
| 2018-12-22 10:15:00 | Study provide evidence to suggest that DSPP may be involved in endoplasmic reticulum (ER) stress mechanisms in oral squamous cell carcinoma, since its downregulation in OSC2 cells led to significant alterations in the levels of major ER stress-associated proteins, and subsequent collapse of the unfolded protein response system. | 30015841 |
| Type | IDs |
|---|---|
| Synonymous | DFNA39, DGI1, DMP3, DPP, DSP |
| Gene |
UniProtKB-ID:
DSPP_HUMAN
UniprotKB:
Q9NZW4
UniParc:
UPI00006BFF57
EMBL:
AF163151,
AF094508,
AC093895
Ensembl:
ENSG00000152591
KO:
hsa:1834
|
| Nucleutide sequences |
EMBL-CDS:
AAD16120.1,
AAF42472.1
Ensembl_TRS:
ENST00000651931
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000498766
RefSeq:
NP_055023.2
|
| Others |
UniRef100:
UniRef100_Q9NZW4
UniRef90:
UniRef90_Q9NZW4
UniRef50:
UniRef50_Q9NZW4
UniGene:
Hs.678914
CCDS:
CCDS43248.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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