| Type | Description |
|---|---|
| Definition | desmoglein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:48:00 | Keratinocyte cadherin desmoglein 1 controls melanocyte behavior through paracrine signaling. | 31563153 |
| 2020-11-21 13:15:00 | The Role of Desmoglein 1 in Gap Junction Turnover Revealed through the Study of SAM Syndrome. | 31465738 |
| 2020-10-24 14:01:00 | Novel mutations in desmoglein 1: focal palmoplantar keratoderma in milder phenotypes. | 30822367 |
| 2020-05-02 11:52:00 | Work exposes a new pathway by which a desmosomal cadherin called Dsg1, which is lost early in head and neck cancer progression, suppresses cancer cell invadopodia formation by scaffolding ErbB2 Interacting Protein and consequent attenuation of EGF/Erk signaling. | 30655320 |
| 2019-12-07 11:21:00 | More than 20 genes have been reported to be associated with PPKs including desmoglein 1 (DSG1) a key molecular component for epidermal adhesion and differentiation. Mal de Meleda (MDM) is a rare inherited autosomal recessive genodermatosis characterized by transgrediens PPK, associated with mutations in the secreted LY6/PLAUR domain containing 1 (SLURP1) gene. | 31443639 |
| Type | IDs |
|---|---|
| Synonymous | CDHF4, DG1, DSG, EPKHE, EPKHIA, PPKS1, SPPK1 |
| Gene |
UniProtKB-ID:
DSG1_HUMAN
UniprotKB:
Q02413
UniParc:
UPI000013CF4C,
UPI0001915156
EMBL:
AK302888,
AF097935,
AC009717,
X56654
Ensembl:
ENSG00000134760
KO:
hsa:1828
|
| Nucleutide sequences |
EMBL-CDS:
AAC83817.1,
CAA39976.1,
BAH13831.1
Ensembl_TRS:
ENST00000257192
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000257192
RefSeq:
NP_001933.2
|
| Others |
UniRef100:
UniRef100_Q02413
UniRef90:
UniRef90_Q02413
UniRef50:
UniRef50_Q02413
UniGene:
Hs.2633
CCDS:
CCDS11896.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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