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18263 Odc1

18263

Odc1

ornithine decarboxylase, structural 1

protein-coding

Mus musculus

基因描述

Type Description
Definition ornithine decarboxylase, structural 1

研究结论

Date Results Publications
2021-03-20 13:34:00 ODC (Ornithine Decarboxylase)-Dependent Putrescine Synthesis Maintains MerTK (MER Expression to Drive Resolution. 33406854
2020-04-18 10:04:00 Amyloid beta may contribute to M1-like activation by disrupting the balance between ODC and AZ in microglia. 30417362
2019-03-30 12:08:00 Findings indicated that ornithine decarboxylase (ODC1) was involved in attenuating the inflammatory response upon stimulation of macrophages, making it a potential therapeutic target for inflammatory diseases. 30217446
2018-04-14 10:33:00 We demonstrate that ornithine decarboxylase (ODC) regulates M1 activation during Helicobacter pylori and Citrobacter rodentium infection. Deletion of Odc in macrophages resulted in increased inflammation and decreased bacterial persistence in mouse models. The enhanced M1 response was due to alterations in histone modifications, resulting in changes in chromatin structure and up-regulated transcription. 28096401
2017-12-09 10:07:00 these data support the hypothesis that TTP plays a role in the post-transcriptional regulation of the ODC mRNA transcript. 27193233

名称对应

Type IDs
Synonymous ODC
Gene
UniProtKB-ID: DCOR_MOUSE
UniprotKB: P00860
UniParc: UPI00000211E4
EMBL: S64539, J03733, EU684749, M12330, M10624, BC059826, BC083122, CH466582, AK139610, X07392, M12331, M20617
Ensembl: ENSMUSG00000011179
KO: mmu:18263
Nucleutide sequences
EMBL-CDS: CAA30301.1, AAA39849.1, ACD81645.1, AAA51638.1, AAB27809.1, BAE24082.1, AAH59826.1, AAA39848.1, AAH83122.1, AAA39846.1, EDK98494.1, AAA39845.1
Ensembl_TRS: ENSMUST00000171737
Protein sequencees
Ensembl_PRO: ENSMUSP00000128661
RefSeq: NP_038642.2, XP_017170479.1
Others
UniRef100: UniRef100_P00860
UniRef90: UniRef90_P00860
UniRef50: UniRef50_P00860
UniGene: Mm.34102, Mm.472891
CCDS: CCDS25829.1

全选

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