| Type | Description |
|---|---|
| Definition | desmocollin 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:00:00 | Desmocollin-2 promotes intestinal mucosal repair by controlling integrin-dependent cell adhesion and migration. | 31967937 |
| 2020-05-16 11:14:00 | Mutation in the DSC2 gene is associated with nevus of Ota with choroidal melanoma. | 31407624 |
| 2019-11-16 13:07:00 | Colocalization analysis using cell compartment trackers revealed that N-glycosylation- deficient DSC2 mutants were retained within the Golgi apparatus. In contrast, elimination of the four O-mannosylation sites or the disulfide bridges in the ECD has no obvious effect on the intracellular protein processing of DSC2. | 30942563 |
| 2018-09-22 10:15:00 | Desmocollin-2 genetic variant contributes to Arrhythmogenic Right Ventricular Cardiomyopathy | 27531918 |
| 2017-12-30 11:04:00 | PKP3 overexpression increases the stability of other desmosomal proteins independently of the increase in DSC2 levels and regulates desmosome formation and stability by a multimodal mechanism affecting transcription, protein stability and cell border localization of desmosomal proteins. | 29146182 |
| Type | IDs |
|---|---|
| Synonymous | ARVD11, CDHF2, DG2, DGII/III, DSC3 |
| Gene |
UniProtKB-ID:
DSC2_HUMAN,
A0A3B3ISU0_HUMAN
UniprotKB:
Q02487,
A0A3B3ISU0
UniParc:
UPI000387BEE9,
UPI000002A848,
UPI00001298F9
EMBL:
AC012417,
X56807,
BC063291,
KF573685
Ensembl:
ENSG00000134755
KO:
hsa:1824
|
| Nucleutide sequences |
EMBL-CDS:
AAH63291.1,
CAA40142.1,
CAA40141.1
Ensembl_TRS:
ENST00000251081,
ENST00000280904,
ENST00000648081
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000280904,
ENSP00000251081,
ENSP00000497441
RefSeq:
NP_077740.1,
XP_005258263.1,
NP_004940.1
|
| Others |
UniRef100:
UniRef100_Q02487
UniRef90:
UniRef90_Q02487
UniRef50:
UniRef50_Q02487
UniGene:
Hs.95612
CCDS:
CCDS11892.1,
CCDS11893.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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