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18216 Ntsr1

18216

Ntsr1

neurotensin receptor 1

protein-coding

Mus musculus

基因描述

Type Description
Definition neurotensin receptor 1

研究结论

Date Results Publications
2020-11-21 13:20:00 Differential allosteric modulation within dopamine D2R - neurotensin NTS1R and D2R - serotonin 5-HT2AR receptor complexes gives bias to intracellular calcium signalling. 31704949
2019-01-12 11:48:00 Collectively, this work reveals a cellular mechanism by which neurotensi can directly engage neurotensin receptor 1-expressing DA neurons to modify dopamine signaling. 29464190
2018-07-28 12:19:00 The weight loss behaviors are mediated by distinct signaling pathways: Nts action via NtsR1 is essential for the anorectic effect of the lateral hypothalamic Nts circuit, but not for regulation of locomotor or drinking behavior. 29241540
2018-05-19 10:45:00 Authors identified a specific subset of VTA DA neurons that express neurotensin receptor-1 (NtsR1) and preferentially comprise mesolimbic, but not mesocortical, DA neurons. 28834751
2017-08-12 12:07:00 Data demonstrate that the NTR1 can modulate the methamphetamine-induced striatal neuronal apoptosis independent of body temperature regulation. Possible mechanisms of NTR1 modulating methamphetamine-induced apoptosis include the regulation of dopamine and glutamate neurotransmission in the striatum. 28130052

名称对应

Type IDs
Synonymous NT-1R, NTR-1, NTR1
Gene
UniProtKB-ID: NTR1_MOUSE, A2ACT4_MOUSE
UniprotKB: O88319, A2ACT4
UniParc: UPI000002962C
EMBL: BC138630, BC138633, AB017027
Ensembl: ENSMUSG00000027568
KO: mmu:18216
Nucleutide sequences
EMBL-CDS: BAA33013.1, AAI38634.1, AAI38631.1
Ensembl_TRS: ENSMUST00000029084, ENSMUST00000170448
Protein sequencees
Ensembl_PRO: ENSMUSP00000127548, ENSMUSP00000029084
RefSeq: NP_061236.1
Others
UniRef100: UniRef100_O88319
UniRef90: UniRef90_P20789
UniRef50: UniRef50_P20789
UniGene: Mm.301712
CCDS: CCDS17177.1

全选

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