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18213 Ntrk3

18213

Ntrk3

neurotrophic tyrosine kinase, receptor, type 3

protein-coding

Mus musculus

基因描述

Type Description
Definition neurotrophic tyrosine kinase, receptor, type 3

研究结论

Date Results Publications
2018-11-10 12:32:00 TrkC signals to the podocyte actin cytoskeleton to induce migration by phosphorylating WAVE2 Erk dependently. This signaling mechanism may be important for TrkC-mediated cytoskeletal dynamics in podocyte disease. 29162704
2018-07-28 12:19:00 In a retinitis pigmentosa mouse model, TrkC activity generates phosphorylated Erk, which upregulates glial TNF-alpha, causing selective neuronal death. 29242588
2016-10-22 10:27:00 our data suggest that Runx3 may play a crucial role in the development of DRGs by regulating the expression of Ntrk3 variants 26061886
2014-12-20 10:45:00 adult homozygous TrkAC knock-in mice displayed severe deficits in acute and tissue injury-induced pain, representing the first viable adult Trk mouse mutant with a pain phenotype 24516396
2014-02-01 10:08:00 TrkC expression in E13.5 VCG neurons requires NeuroD and that TrkC expression may be necessary for the normal migration and innervations of those neurons. 23652629

名称对应

Type IDs
Synonymous AW125844, Ntrk3_tv3, TrkC
Gene
UniProtKB-ID: NTRK3_MOUSE, A0A0A6YWF9_MOUSE, A0A0A6YWL7_MOUSE, Q3TNY3_MOUSE
UniprotKB: Q6VNS1, A0A0A6YWF9, A0A0A6YWL7, Q3TNY3
UniParc: UPI00053BD81E, UPI000002985F, UPI000002B612, UPI000002B611, UPI00005B20E2, UPI000047A3A7
EMBL: AC108420, BC139764, AC156556, AK164887, AC115868, AF035399, AC110225, AY336094, AC121082, AF035400
Ensembl: ENSMUSG00000059146
KO: mmu:18213
Nucleutide sequences
EMBL-CDS: AAC72290.1, AAI39765.1, AAP94280.1, AAC72289.1, BAE37954.1
Ensembl_TRS: ENSMUST00000039431, ENSMUST00000039438, ENSMUST00000193002, ENSMUST00000195262
Protein sequencees
Ensembl_PRO: ENSMUSP00000038324, ENSMUSP00000037909, ENSMUSP00000141534, ENSMUSP00000141599
RefSeq: NP_877961.1, XP_036008660.1, XP_011249119.1, XP_006540755.1, NP_032772.3, XP_036008659.1
Others
UniRef100: UniRef100_A0A0A6YWL7, UniRef100_Q6VNS1, UniRef100_A0A2R8MR76, UniRef100_A0A0A6YWF9
UniRef90: UniRef90_Q16288, UniRef90_Q03351, UniRef90_A0A2R8MR76
UniRef50: UniRef50_Q16288
UniGene: Mm.33496, Mm.421361
CCDS: CCDS21372.1, CCDS21371.1

全选

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研究热度

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