| Type | Description |
|---|---|
| Definition | nth (endonuclease III)-like 1 (E.coli) |
| Date | Results | Publications |
|---|---|---|
| 2014-03-22 10:37:00 | Toxicity, induced by tert-butyl-hydroperoxide and potassium bromate, differs in base excision repair proficient (Mpg (+/+), Nth1 (+/+)) and deficient (Mpg (-/-), Nth1 (-/-)) mouse embryonic fibroblasts following Msh2 knockdown, was examined. | 23984319 |
| 2014-01-11 11:15:00 | These results suggest that Nth1 plays an important role in telomere maintenance and base repair against oxidative stress-induced base modifications. | 23874233 |
| 2012-09-01 10:19:00 | deficiencies in Ogg1 and/or Nth1 do not lead to decreased DNA double strand breaks | 22536455 |
| 2010-01-21 00:00:00 | To determine the significance of thymine glycol repair in mammals, a mouse model with mutated mNth1, a homolog of nth, was made by gene targeting. Mutant mouse liver, instead of mNTH1 activity, had at least 2 novel DNA glycosylase activities against Tg. | 12093749 |
| 2010-01-21 00:00:00 | The high incidence of tumors in Nth1-/-Neil1-/- mice together with the activating mutation in the K-ras gene of their pulmonary tumors, reveal for the first time, the existence of mutagenic and carcinogenic oxidative damage to DNA which is not 8-OH-Gua. | 19346169 |
| Type | IDs |
|---|---|
| Synonymous | Nth1, Octs3 |
| Gene |
UniProtKB-ID:
NTH_MOUSE
UniprotKB:
O35980
UniParc:
UPI000002687C
EMBL:
AC132367,
AB009371,
Y09688,
AB006812,
AK033701,
AJ001617
Ensembl:
ENSMUSG00000041429
KO:
mmu:18207
|
| Nucleutide sequences |
EMBL-CDS:
BAA22080.1,
CAA70866.1,
BAA28846.1,
CAB65239.1
Ensembl_TRS:
ENSMUST00000047611
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000047413
RefSeq:
NP_001344544.1,
NP_032769.2,
XP_006523882.1
|
| Others |
UniRef100:
UniRef100_O35980
UniRef90:
UniRef90_O35980
UniRef50:
UniRef50_O35980
UniGene:
Mm.148315
CCDS:
CCDS28487.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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