| Type | Description |
|---|---|
| Definition | muscle, skeletal, receptor tyrosine kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:07:00 | Muscle specific kinase protects dystrophic mdx mouse muscles from eccentric contraction-induced loss of force-producing capacity. | 31340406 |
| 2019-08-03 11:49:00 | During development, MuSK serves as a signaling hub, coordinating the alignment of the pre- and postsynaptic components of the synapse. Adult mice that received repeated daily injections of IgG from anti-MuSK(+) myasthenia gravis patients developed muscle weakness, associated with neuromuscular transmission failure. Review. | 29125188 |
| 2019-03-09 10:06:00 | Agrin induced an Lrp4-independent increase in dendritic branch complexity, an Lrp4-dependent increase of excitatory synaptic puncta and an Lrp4- and MuSK-independent decrease in the density of puncta containing inhibitory synapse-associated proteins. Results establish selective roles for agrin, Lrp4 and MuSK during dendritogenesis and synaptogenesis in cultured CNS neurons. | 30385274 |
| 2017-11-26 01:48:00 | Gene expression profiling showed that MuSK was required for the BMP4-induced expression of a subset of genes in myoblasts, including regulator of G protein signaling 4 (Rgs4). | 27601729 |
| 2017-05-20 14:11:00 | These mice showed only marginal activation of MuSK and died by 3 weeks of age apparently due to an abnormally small number and size of neuromuscular junction (NMJs). | 28069867 |
| Type | IDs |
|---|---|
| Synonymous | Mdk4, Mlk, Nsk1, Nsk2, Nsk3 |
| Gene |
UniProtKB-ID:
MUSK_MOUSE,
Q32S50_MOUSE,
Q32S49_MOUSE,
E9PVV8_MOUSE,
Q32SD3_MOUSE,
Q1XD56_MOUSE,
Q497X0_MOUSE
UniprotKB:
Q61006,
Q32S50,
Q32S49,
E9PVV8,
Q32SD3,
Q1XD56,
Q497X0
UniParc:
UPI00003BF75A,
UPI00005D6BC7,
UPI00000E6663,
UPI00015DF265,
UPI0000D4F8BF,
UPI00003BF75B,
UPI0000574FBB,
UPI00000E8272
EMBL:
AY955298,
U37708,
AY956403,
AY956404,
BC100342,
AL805969,
AL807748,
X86445,
AY955297,
X86444,
U37709,
AY360453
Ensembl:
ENSMUSG00000057280
KO:
mmu:18198
|
| Nucleutide sequences |
EMBL-CDS:
AAA79204.1,
CAA60165.1,
AAA79203.1,
CAA60166.1,
AAY40321.1,
AAY40322.1,
AAY40319.1,
AAR12275.1,
AAI00343.1,
AAY40320.1
Ensembl_TRS:
ENSMUST00000084578,
ENSMUST00000102893,
ENSMUST00000098057,
ENSMUST00000177951
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000081625,
ENSMUSP00000099957,
ENSMUSP00000095665,
ENSMUSP00000136696
RefSeq:
NP_001159468.1,
NP_001032206.1,
NP_001032204.2,
NP_035074.2,
NP_001032205.1,
XP_006537724.1,
NP_001032207.1,
XP_006537722.1
|
| Others |
UniRef100:
UniRef100_E9PVV8,
UniRef100_Q497X0,
UniRef100_Q1XD56,
UniRef100_Q61006,
UniRef100_Q32SD3,
UniRef100_Q32S49
UniRef90:
UniRef90_Q61006-3,
UniRef90_Q1XD56,
UniRef90_Q61006
UniRef50:
UniRef50_Q61006-3,
UniRef50_Q1XD56,
UniRef50_Q61006
UniGene:
Mm.16148
CCDS:
CCDS18210.1,
CCDS18211.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员