| Type | Description |
|---|---|
| Definition | nuclear receptor-binding SET-domain protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:49:00 | Investigating cortical features of Sotos syndrome using mice heterozygous for Nsd1. | 31909872 |
| 2020-11-28 13:16:00 | NSD1-deposited H3K36me2 directs de novo methylation in the mouse male germline and counteracts Polycomb-associated silencing. | 32929285 |
| 2020-08-22 15:28:00 | Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia. | 32533074 |
| 2019-02-09 10:56:00 | Nsd1 is a key modulator of PRC2 function required for regulating the demarcation of genome-wide H3K27me2 and H3K27me3 domains in embryonic stem cells. | 29606589 |
| 2014-10-04 10:46:00 | Silencing of Nsd1 followed by LLO stimulation led to increased caspase-1 activation, enhanced post-translational maturation of IL-1beta and IL-18 and elevated pyroptosis, a form of cell death associated with inflammation. | 24058709 |
| Type | IDs |
|---|---|
| Synonymous | AI528500, KMT3B |
| Gene |
UniProtKB-ID:
E9QAE4_MOUSE,
Q3UL03_MOUSE
UniprotKB:
E9QAE4,
Q3UL03
UniParc:
UPI00005AC468,
UPI0000606D57
EMBL:
AC160958,
AK145783
Ensembl:
ENSMUSG00000021488
KO:
mmu:18193
|
| Nucleutide sequences |
EMBL-CDS:
BAE26648.1
Ensembl_TRS:
ENSMUST00000099490
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000097089
RefSeq:
XP_036013802.1,
XP_006517200.1,
XP_006517209.1,
XP_036013803.1,
XP_036013801.1,
XP_006517206.1,
XP_006517199.1,
XP_030103042.1,
XP_036013800.1,
XP_030103044.1,
XP_006517198.1,
XP_006517210.1,
XP_030103047.1,
XP_030103045.1,
XP_036013799.1,
XP_006517207.1,
XP_006517201.1,
NP_032765.3,
XP_006517203.1,
XP_006517197.1,
XP_030103046.1,
XP_030103041.1,
XP_006517205.1,
XP_036013798.1,
XP_006517211.1,
XP_006517204.1
|
| Others |
UniRef100:
UniRef100_E9QAE4
UniRef90:
UniRef90_E9QAE4
UniRef50:
UniRef50_Q96L73
UniGene:
Mm.12964,
Mm.168965
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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