| Type | Description |
|---|---|
| Definition | neurexin II |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 12:06:00 | Presynaptic alternative splicing of neurexin-2 at SS4 had no effect on post-synaptic NMDA- or AMPA-receptor-mediated responses. | 31005376 |
| 2019-04-13 11:50:00 | Neurexin deletion induces atypical structural connectivity within socially relevant brain regions. | 30858964 |
| 2017-12-30 12:45:00 | IgSF21 interacts with neurexin2alpha to induce presynaptic differentiation of inhibitory synapses, and mice lacking IgSF21 exhibit deficits in inhibitory synaptic transmission | 28864826 |
| 2017-07-29 12:57:00 | After pan-neurexin deletions, we observed in these synapses severe but dramatically different synaptic phenotypes that ranged from major impairments in their distribution and function (climbing-fiber synapses) to large decreases in synapse numbers (parvalbumin-positive synapses) and severe alterations in action potential-induced presynaptic Ca(2+) transients (somatostatin-positive synapses). | 28472659 |
| 2017-06-10 12:28:00 | The results indicate that Nrx2alpha and NL1 are targets of Abeta oligomers and that prevention of this interaction reduces the deleterious impact of Abeta oligomers on synapses and cognition. | 28283575 |
| Type | IDs |
|---|---|
| Synonymous | 6430591O13Rik, mKIAA0921 |
| Gene |
UniProtKB-ID:
A0A494B8Y4_MOUSE,
E9Q5N7_MOUSE,
E9PUM9_MOUSE
UniprotKB:
A0A494B8Y4,
E9Q5N7,
E9PUM9
UniParc:
UPI00004F8E20,
UPI0001F78AF6,
UPI000058AE33
EMBL:
AC124394,
AC167245
Ensembl:
ENSMUSG00000033768
KO:
mmu:18190
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000236635,
ENSMUST00000235714,
ENSMUST00000077182,
ENSMUST00000113462
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000157405,
ENSMUSP00000158360,
ENSMUSP00000076424,
ENSMUSP00000109089
RefSeq:
NP_001192164.1,
NP_064649.2,
NP_001356292.1,
NP_001192163.1
|
| Others |
UniRef100:
UniRef100_E9PUM9,
UniRef100_E9Q5N7,
UniRef100_A0A494B8Y4
UniRef90:
UniRef90_E9Q7X7,
UniRef90_E9PUM9
UniRef50:
UniRef50_E9Q7X7,
UniRef50_Q07310
UniGene:
Mm.329616,
Mm.414022
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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