| Type | Description |
|---|---|
| Definition | developmentally regulated GTP binding protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-25 11:44:00 | Knockdown of DRG2 in HeLa cells treated with epidermal growth factor (EGF) affects microtubule dynamics, perinuclear Golgi stacking, and cell migration. | 31199931 |
| 2019-02-23 11:26:00 | Using immunoprecipitation, authors show that DRG2 interacts with tau, which regulates microtubule polymerization. Collectively, these data demonstrate that DRG2 may aid in affecting microtubule dynamics in HeLa cells. | 30453731 |
| 2019-01-05 10:47:00 | Results show that the SNP (rs2257609 C>T) located in the intron region of SLC5A10 variant does not affect the expression of SLC5A10 mRNA, but alters the mRNA expression and promoter activity of DRG2. It is significantly associated with worse overall and disease-free survival of non-small-cell lung cancer (NSCLC) patients. | 30281872 |
| 2017-06-24 11:14:00 | Taken together, our data demonstrate that DRG2 acts as a regulator of mitochondrial fission by controlling the expression of Drp1. | 28363867 |
| 2017-04-29 10:29:00 | Authors observed that knockdown of DRG2 in HeLa cells affected growth in a wound-healing assay, and tumorigenicity in nude mice xenografts. | 27669826 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DRG2_HUMAN,
A8MZF9_HUMAN
UniprotKB:
P55039,
A8MZF9
UniParc:
UPI0000D4D528,
UPI000012987D
EMBL:
AC087164,
AK313362,
BC000493,
X80754,
BT006976,
CH471196
Ensembl:
ENSG00000108591
KO:
hsa:1819
|
| Nucleutide sequences |
EMBL-CDS:
BAG36162.1,
EAW55669.1,
AAH00493.1,
AAP35622.1,
CAA56730.1
Ensembl_TRS:
ENST00000225729,
ENST00000395726
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000225729,
ENSP00000379076
RefSeq:
NP_001317073.1,
XP_005256556.1,
NP_001379.1,
XP_005256557.1,
XP_016879786.1,
XP_011522006.1,
XP_011522008.1,
XP_011522009.1,
XP_016879785.1
|
| Others |
UniRef100:
UniRef100_A8MZF9,
UniRef100_P55039
UniRef90:
UniRef90_A8MZF9,
UniRef90_P55039
UniRef50:
UniRef50_P55039
UniGene:
Hs.78582
CCDS:
CCDS11191.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员