| Type | Description |
|---|---|
| Definition | neural retina leucine zipper gene |
| Date | Results | Publications |
|---|---|---|
| 2019-06-01 12:02:00 | In the Nphp5-/- and cone-only Nphp5-/-; Nrl-/- mice, cone outer segments did not form, but mutant cones continued to express cone pigments in the inner segments without obvious signs of cone cell death. | 30713422 |
| 2019-03-30 11:49:00 | The Frmd4bTvrm222 allele was also found to suppress outer nuclear layer (ONL) rosettes in Nrl-/- mice. Fragmentation of the external limiting membrane (ELM), normally observed in rd7 and Nrl-/-mouse retinas, was absent in the presence of the Frmd4bTvrm222 allele | 29947801 |
| 2018-12-22 11:01:00 | that two photoreceptor-specific transcription factors, NRL and CRX, are master regulators of this program and are required for tumor maintenance in this subgroup | 29533784 |
| 2018-11-17 11:33:00 | Following Nrl disruption, rods gain partial features of cones and present with improved survival in the presence of mutations in rod-specific genes, consequently preventing secondary cone degeneration. In three different mouse models of retinal degeneration, the treatment substantially improves rod survival and preserves cone function. | 28291770 |
| 2018-07-28 10:13:00 | Nrl is posttranscriptionally regulated to facilitate the generation of other cell types in retina | 27878762 |
| Type | IDs |
|---|---|
| Synonymous | D14H14S46E |
| Gene |
UniProtKB-ID:
NRL_MOUSE,
Q8C8Y1_MOUSE,
Q543Y0_MOUSE
UniprotKB:
P54846,
Q8C8Y1,
Q543Y0
UniParc:
UPI000000151C,
UPI00000E9813
EMBL:
AK044316,
BC031440,
AK044275,
AK044244,
L14935
Ensembl:
ENSMUSG00000040632
KO:
mmu:18185
|
| Nucleutide sequences |
EMBL-CDS:
AAA16843.1,
AAH31440.1,
BAC31838.1,
BAC31863.1,
BAC31849.1
Ensembl_TRS:
ENSMUST00000111404,
ENSMUST00000178694,
ENSMUST00000062232
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000054457,
ENSMUSP00000107035,
ENSMUSP00000136445
RefSeq:
NP_001258846.1,
NP_032762.1,
NP_001129546.1,
XP_006518751.1,
NP_001258845.1
|
| Others |
UniRef100:
UniRef100_P54846,
UniRef100_Q8C8Y1
UniRef90:
UniRef90_P54846
UniRef50:
UniRef50_P54846
UniGene:
Mm.20422
CCDS:
CCDS27113.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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