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181728 mec-4

181728

mec-4

Degenerin mec-4

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Degenerin mec-4

研究结论

Date Results Publications
2020-09-05 13:53:00 Progressive recruitment of distal MEC-4 channels determines touch response strength in C. elegans. 31533952
2019-07-06 10:05:00 we found that the worm's response to ultrasound pulses rests on the expression of MEC-4, a DEG/ENaC/ASIC ion channel required for touch sensation 29463641
2019-03-16 11:12:00 Here we demonstrate that diapause promotes the complete morphological regeneration of truncated touch receptor neuron (TRN) axons expressing a neurotoxic MEC-4(d) DEG/ENaC channel 30640919
2017-01-28 10:12:00 MEC-6 and POML-1 interact with MEC-4 to facilitate expression and localization of MEC-4 on the cell surface. Thus MEC-6 and POML-1 act more like chaperones for MEC-4 than channel components. 26941331
2016-01-16 11:10:00 MEC-10, but not MEC-6, forms puncta in touch receptor neurites that colocalize with MEC-4 when MEC-4 is overexpressed in the touch receptor neurons 26324944

名称对应

Type IDs
Gene
UniProtKB-ID: MEC4_CAEEL
UniprotKB: P24612
UniParc: UPI000012EEAC
EMBL: U53669, FO081053, X58982
EnsemblGenome: WBGene00003168
KO: cel:CELE_T01C8.7
Nucleutide sequences
EMBL-CDS: AAC47265.1, CAA41731.1, CCD68838.1
Gene_ORFName: T01C8.7
EnsemblGenome_TRS: T01C8.7.1, T01C8.7.2
Protein sequencees
EnsemblGenome_PRO: T01C8.7.1, T01C8.7.2
RefSeq: NP_510712.2
Others
UniRef100: UniRef100_P24612
UniRef90: UniRef90_P24612
UniRef50: UniRef50_P24612
UniGene: Cel.634

全选

研究热度

研究结论
热点单位
排名 科研单位 文献
1

Columbia University

9
2

The State University of New Jersey

4
3

Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute

3
4

Rutgers University

2
5

Stanford University School of Medicine

2
热点人员
排名 研究人员 文献
1

Martin Chalfie

8
2

Miriam B Goodman

6
3

C Andrea Yao

3
4

Robert O'Hagan

3
5

M Chalfie

3
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