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18168 Npy5r

18168

Npy5r

neuropeptide Y receptor Y5

protein-coding

Mus musculus

基因描述

Type Description
Definition neuropeptide Y receptor Y5

研究结论

Date Results Publications
2021-02-02 13:22:00 Molecular crosstalk between Y5 receptor and neuropeptide Y drives liver cancer. 31999643
2018-06-09 11:16:00 Study suggests that PYY3-36 mediated signalling via Y5 receptors may counteract the anorectic effects that it mediates via the Y2 receptor, consequently lowering bodyweight in the absence of Y5 signalling. 28485050
2017-11-11 12:55:00 NPY and agonists of Y2R and Y5R may be neuroprotective against oxygen-glucose deprivation-induced neuronal cell death in primary cortical cell cultures after delayed treatment. A Y2R agonist not only diminished transient cerebral ischemia-induced neuronal injury, but also improved functional outcome after delayed treatment. Y5 and especially Y2 receptors may be promising targets for neuroprotection against ischemic damage 28057538
2017-08-12 10:55:00 Y5-immunoreactivity was distributed widely in mouse brain, and the Y5 protein localization was mostly observed in the somata of the Y5 neurons. By purifying the polyclonal antibody with fixed knockout mouse tissue, the precise Y5 localization became obvious in mouse brain, especially in areas other than the hypothalamic area. 27984021
2015-07-25 10:04:00 Npy1r(Y5R-/-) mice show increased anxiety-related behavior but no changes in hypothalamus-pituitary-adrenocortical axis activity or in body weight growth, independently of gender and mouse strain used as foster mothers. Also, Npy1r(Y5R-/-) mice of both genders display increased spatial reference memory in the Morris water maze test. 24548641

名称对应

Type IDs
Synonymous NPY5-R, NPYY5-R, Y5R
Gene
UniProtKB-ID: NPY5R_MOUSE, Q543U8_MOUSE
UniprotKB: O70342, Q543U8
UniParc: UPI0000004074
EMBL: AF049329, BC116978, AK045587, AF022948, BC116976, AB001346
Ensembl: ENSMUSG00000044014
KO: mmu:18168
Nucleutide sequences
EMBL-CDS: BAA89538.1, AAB81829.1, AAC17839.1, BAC32426.1, AAI16977.1, AAI16979.1
Ensembl_TRS: ENSMUST00000211920, ENSMUST00000070810, ENSMUST00000212563
Protein sequencees
Ensembl_PRO: ENSMUSP00000065157, ENSMUSP00000148410, ENSMUSP00000148589
RefSeq: NP_001345886.1, NP_001345887.1, NP_057917.2, XP_036009706.1
Others
UniRef100: UniRef100_O70342
UniRef90: UniRef90_Q63634
UniRef50: UniRef50_Q63634
UniGene: Mm.10685
CCDS: CCDS22335.1

全选

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