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1816 DRD5

1816

DRD5

dopamine receptor D5

protein-coding

Homo sapiens

基因描述

Type Description
Definition dopamine receptor D5

研究结论

Date Results Publications
2020-11-28 13:16:00 Hypermethylation of DRD5 Promoter Is a Biomarker Across 12 Cancer Types. 32907377
2020-11-21 13:29:00 The effects of dopamine receptor genes on the trajectories of sport participation from adolescence through young adulthood. 32183536
2020-07-25 13:01:00 These suggest that hD5R(F173L) increases blood pressure, in part, by decreasing renal thioredoxin 1 expression and increasing reactive oxygen species production. Hyperphosphorylation of hD5R(F173L), with its dissociation from Galphas and Galphaq, is the key factor in impaired D5R function of hD5R(F173L)-TG mice. 30957627
2020-05-16 12:51:00 These results implicate DRD5 as a negative regulator of DRD2 signaling and tumor sensitivity to ONC201 DRD2 antagonism. 30559168
2018-12-22 11:09:00 Dopamine D5 receptor may play an important role in the preservation of normal heart function by inhibiting the production of reactive oxygen species, via inhibition of NADPH oxidase, Nrf2 degradation, and ERK1/2/JNK pathways. 30153650

名称对应

Type IDs
Synonymous DBDR, DRD1B, DRD1L2
Gene
UniProtKB-ID: DRD5_HUMAN
UniprotKB: P21918
UniParc: UPI000004E905
EMBL: AK313897, BC009748, M67439, X58454, CH471069, AY136750
Ensembl: ENSG00000169676
KO: hsa:1816
Nucleutide sequences
EMBL-CDS: CAA41360.1, EAW92679.1, AAA52329.1, AAH09748.1, BAG36620.1, AAN01276.1
Ensembl_TRS: ENST00000304374
Protein sequencees
Ensembl_PRO: ENSP00000306129
RefSeq: NP_000789.1
Others
UniRef100: UniRef100_P21918
UniRef90: UniRef90_P21918
UniRef50: UniRef50_P21918
UniGene: Hs.380681
CCDS: CCDS3405.1

全选

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研究热度

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