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181576 atf-5

181576

atf-5

ATF (cAMP-dependent transcription factor) family

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition ATF (cAMP-dependent transcription factor) family

研究结论

Date Results Publications
2018-06-16 11:23:00 Study reports that reduced levels of ATF5 in brain of Huntington's disease patients, probably due to its sequestration into the characteristic PolyQ containing neuronal inclusion bodies, correlates with decreased levels of the antiapoptotic protein MCL1, a transcriptional target of ATF5. Also provides evidence of decreased ATF5 being deleterious by rendering neurons more vulnerable to polyQ-induced apoptosis. 28861715

名称对应

Type IDs
Gene
UniProtKB-ID: Q22156_CAEEL
UniprotKB: Q22156
UniParc: UPI000007C102
EMBL: BX284606
EnsemblGenome: WBGene00000221
KO: cel:CELE_T04C10.4
Nucleutide sequences
EMBL-CDS: CAA93757.1
Gene_ORFName: T04C10.4, CELE_T04C10.4
Protein sequencees
RefSeq: NP_510456.1
Others
UniRef100: UniRef100_Q22156
UniRef90: UniRef90_Q22156
UniRef50: UniRef50_Q22156
UniGene: Cel.6024

全选

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研究热度

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