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181484 nlg-1

181484

nlg-1

Neuroligin-1

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Neuroligin-1

研究结论

Date Results Publications
2021-03-13 13:18:00 The Ig-like domain of Punctin/MADD-4 is the primary determinant for interaction with the ectodomain of neuroligin NLG-1. 32928959
2020-04-11 12:38:00 The authors show that a C elegans mutant in the single gene orthologous to human neuroligins, nlg-1, is defective in food-induced pumping. This was not due to an inability to sense food, as nlg-1 mutants were not defective in chemotaxis towards bacteria. In addition, we found that neuroligin is widely expressed in the nervous system. 30559302
2019-11-16 12:57:00 Loss of nlg-1 suppresses the hpo-30 mutant phenotype.NLG-1 functions downstream of HPO-30 to maintain the LAChR-dependent functions at the neuromuscular junction.Elevated NLG-1 levels result in decreased LAChRs at the NMJ. 29950505
2018-03-26 10:02:00 Neuroligin mutants are defective in a subset of sensory behaviors and sensory processing, and are hypersensitive to oxidative stress and mercury compounds.[Neuroligin-1] 20083577
2015-08-29 11:18:00 The results highlight a developmental regulation of C. elegans nlg-1 that could play a key role in the assembly of synaptic protein complexes during the early stages of nervous system development. 25726726

名称对应

Type IDs
Gene
UniProtKB-ID: NLGN1_CAEEL, A0A0K3AT91_CAEEL, G5ECG6_CAEEL, A0A0K3AT61_CAEEL, A0A0K3AVK6_CAEEL, A0A0K3AVG1_CAEEL, G5EED7_CAEEL
UniprotKB: Q9XTG1, A0A0K3AT91, G5ECG6, A0A0K3AT61, A0A0K3AVK6, A0A0K3AVG1, G5EED7
UniParc: UPI0006454655, UPI0001F5536A, UPI00064545C0, UPI0001F5536B, UPI00064545C5, UPI000645466C, UPI000007BBB6, UPI0000086572
EMBL: BX284606, AL023827, Z70266
EnsemblGenome: WBGene00006412
KO: cel:CELE_C40C9.5
Nucleutide sequences
EMBL-CDS: CAD57691.1, CAA94208.1, CTQ87046.1, CBZ01784.1, CTQ87016.1, CTQ87047.1, CTQ87017.1, CBZ01785.1
Gene_ORFName: C40C9.5, C40C9.5, CELE_C40C9.5, CELE_C40C9.5, C40C9.5, C40C9.5, CELE_C40C9.5, C40C9.5, CELE_C40C9.5, CELE_C40C9.5, C40C9.5, CELE_C40C9.5, C40C9.5
EnsemblGenome_TRS: C40C9.5b.1, C40C9.5a.1
Protein sequencees
EnsemblGenome_PRO: C40C9.5a.1, C40C9.5b.1
RefSeq: NP_001300336.1, NP_001300305.1, NP_872254.1, NP_001257225.1, NP_001359729.1, NP_001257226.1, NP_001300335.1, NP_510283.1, NP_001300306.1
Others
UniRef100: UniRef100_Q9XTG1, UniRef100_G5ECG6, UniRef100_A0A0K3AT61, UniRef100_A0A0K3AVG1, UniRef100_G5EED7
UniRef90: UniRef90_Q9XTG1
UniRef50: UniRef50_Q9XTG1
UniGene: Cel.5537

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