| Type | Description |
|---|---|
| Definition | Eukaryotic translation initiation factor 2-alpha kinase pek-1 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-13 20:20:00 | In conclusion, we identified PEK-1 as a mediator of hormesis in the mev-1 mutant of C. elegans which is induced by simultaneous inhibition of XBP-1 and its splicing activator IRE-1 and mediated through activation of the proteasome. | 27055592 |
| 2012-03-17 11:44:00 | Our data suggest that the negative feedback loops involving the activation of IRE-1-XBP-1 and PEK-1 pathways serve essential roles, not only at the extremes of ER stress, but also in the maintenance of ER homeostasis under physiological conditions. | 22125500 |
| 2010-01-21 00:00:00 | the salt bridge interaction and dimer interface observed in the PKR structure is critical for the activity of PKR, GCN2, and PERK | 17202131 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
E2AKA_CAEEL
UniprotKB:
Q19192
UniParc:
UPI0000129AC6
EMBL:
Z68104,
AF435953,
AF193341,
Z66563
EnsemblGenome:
WBGene00003970
KO:
cel:CELE_F46C3.1
|
| Nucleutide sequences |
EMBL-CDS:
AAF61201.1,
AAL30829.1,
CAA91470.1
Gene_ORFName:
F46C3.1
EnsemblGenome_TRS:
F46C3.1.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F46C3.1.1
RefSeq:
NP_509912.1
|
| Others |
UniRef100:
UniRef100_Q19192
UniRef90:
UniRef90_Q19192
UniRef50:
UniRef50_Q19192
UniGene:
Cel.7299
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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