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18133 Ccn3

18133

Ccn3

cellular communication network factor 3

protein-coding

Mus musculus

基因描述

Type Description
Definition cellular communication network factor 3

研究结论

Date Results Publications
2021-02-27 13:48:00 CCN3 (NOV) Drives Degradative Changes in Aging Articular Cartilage. 33066270
2019-12-14 11:43:00 our findings suggested that CCN3 significantly inhibited the osteogenic differentiation of mouse embryonic fibroblasts. The inhibitory effect of CCN3 was mainly through the inhibition of BMP signaling and the mutual inhibition with DLL1, so as to inhibit the expression of Hey1, the target gene shared by BMP and Notch signaling pathways. 30538222
2018-02-24 10:26:00 Taken together, our results suggest that palmitoylation by ZDHHC22 at C241 in the CCN3 TSP1 domain may be required for the secretion of CCN3. Aberrant palmitoylation induces intracellular accumulation of CCN3, inhibiting neuronal axon growth. 29287726
2017-08-26 11:03:00 Administration of EET alters Wnt1, NOV, and HO-1 signaling to prevent obesity-induced cardiomyopathy in obese mice. 28576832
2017-06-10 11:40:00 results show that NOV is a new adipocytokine that could be involved in obesity-associated insulin-resistance. 27284105

名称对应

Type IDs
Synonymous C130088N23Rik, Nov
Gene
UniProtKB-ID: CCN3_MOUSE
UniprotKB: Q64299
UniParc: UPI0000001853
EMBL: AK039481, X96585, BC003774, AK081944, X97863, Y09257
Ensembl: ENSMUSG00000037362
KO: mmu:18133
Nucleutide sequences
EMBL-CDS: CAA65404.1, AAH03774.1, CAA70454.1, CAA66457.1, BAC38378.1, BAC30363.1
Ensembl_TRS: ENSMUST00000050027
Protein sequencees
Ensembl_PRO: ENSMUSP00000054389
RefSeq: NP_035060.1
Others
UniRef100: UniRef100_Q64299
UniRef90: UniRef90_Q64299
UniRef50: UniRef50_P48745
UniGene: Mm.5167
CCDS: CCDS27471.1

全选

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研究热度

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