| Type | Description |
|---|---|
| Definition | von Hippel-Lindau tumor suppressor homolog |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 11:56:00 | The authors identified vhl-1 as a genetic modifier and mitochondria-targeting antioxidants as rescuing pharmacological agents for this previously undescribed dopamine neuron subtype-specific neurodegeneration in C. elegans. | 30945137 |
| 2018-07-28 12:19:00 | ELC-2 and the von Hippel-Lindau protein VHL-1, components of an Elongin-Cullin-SOCS box (ECS) E3 ubiquitin ligase, modulate feeding behavior after experiencing stress. | 29241538 |
| 2010-01-21 00:00:00 | The Caenorhabditis elegans rhy-1 gene inhibits hif-1 activity in a negative feedback loop that does not include vhl-1. | 16980385 |
| 2010-01-21 00:00:00 | loss of VHL-1 increased life span; deletion of HIF-1 was epistatic to VHL-1, indicating HIF-1 acts downstream of VHL-1 to modulate aging; VHL-1 & HIF-1 control longevity by a mechanism distinct from dietary restriction & insulin-like signaling | 19372390 |
| 2010-01-21 00:00:00 | there is a discrete HIF-1-independent function of VHL-1 that is connected with extracellular matrix function | 15361934 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
VHL_CAEEL
UniprotKB:
Q19213
UniParc:
UPI0000078B9A
EMBL:
Z66561
EnsemblGenome:
WBGene00006922
KO:
cel:CELE_F08G12.4
|
| Nucleutide sequences |
EMBL-CDS:
CAA91456.1
Gene_ORFName:
F08G12.4
EnsemblGenome_TRS:
F08G12.4.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F08G12.4.1
RefSeq:
NP_509889.1
|
| Others |
UniRef100:
UniRef100_Q19213
UniRef90:
UniRef90_Q19213
UniRef50:
UniRef50_Q19213
UniGene:
Cel.11039
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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