| Type | Description |
|---|---|
| Definition | notch 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:36:00 | Notch4 activation aggravates NF-kappaB-mediated inflammation in a mouse model of HIV-1-associated nephropathy | 31727625 |
| 2019-09-21 10:05:00 | Jag1 on alveolar macrophages interacts with Notch 4 on naive allergen-specific T cells to promote TH2 and TH17 cell differentiation | 29627423 |
| 2019-09-14 12:11:00 | Notch4 inhibited Mycobacterium tuberculosis-induced production of proinflammatory cytokines by interaction with TAK1 and inhibition of its activation. | 29228365 |
| 2019-08-03 12:22:00 | Int3 activates NF-kappaB in HC11 cells in absence of Rbpj through an association with the IKK signalosome. Int3 induced the canonical NF-kappaB activity and P50 phosphorylation in HC11 cells without altering the NF-kappaB2 pathway. The minimal domain within the Int3 protein required to activate NF-kappaB consists of the CDC10/Ankyrin (ANK) repeats domain. | 29057904 |
| 2018-01-13 13:56:00 | Sirt6 inhibits Notch1 and Notch4 transcription by deacetylating histone H3K9. | 28871079 |
| Type | IDs |
|---|---|
| Synonymous | Int-3, Int3, N4 |
| Gene |
UniProtKB-ID:
NOTC4_MOUSE
UniprotKB:
P31695
UniParc:
UPI000016C7F1
EMBL:
AB016772,
AB016771,
U43691,
AB016774,
AB016773,
AF030001,
M80456,
CT009767
Ensembl:
ENSMUSG00000015468
KO:
mmu:18132
|
| Nucleutide sequences |
EMBL-CDS:
BAA32281.1,
AAB38377.1,
BAA32283.1,
BAA32285.1,
CAM18615.1,
AAC52630.1,
AAB82004.1,
AAC52631.1,
BAA32284.1
Ensembl_TRS:
ENSMUST00000015612
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000015612
RefSeq:
NP_035059.2,
XP_006523861.1,
XP_036016259.1
|
| Others |
UniRef100:
UniRef100_P31695
UniRef90:
UniRef90_P31695
UniRef50:
UniRef50_Q99466
UniGene:
Mm.173813
CCDS:
CCDS28647.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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