| Type | Description |
|---|---|
| Definition | nicotinamide N-methyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 10:30:00 | Glucose availability regulates Nnmt expression in adipocytes. | 32112869 |
| 2019-10-12 11:10:00 | These data indicate that NNMT links the NAD(+) and methionine metabolic pathways and promotes liver steatosis and fibrosis. | 29872122 |
| 2019-07-20 10:59:00 | by co-opting the enzymes of the methionine cycle, Nnmt aids the recycling of homocysteine to S-adenosylmethionine for another round of methylation. | 30226369 |
| 2017-09-02 12:48:00 | Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide have been presented. | 28720493 |
| 2014-05-17 15:40:00 | NNMT is a novel regulator of histone methylation, polyamine flux and NAD(+)-dependent SIRT1 signalling, and is a unique and attractive target for treating obesity and type 2 diabetes | 24717514 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
NNMT_MOUSE,
D3YX59_MOUSE,
Q9D9X3_MOUSE
UniprotKB:
O55239,
D3YX59,
Q9D9X3
UniParc:
UPI0000001A59,
UPI00000E70E4,
UPI0000194CB7
EMBL:
AF029756,
AC113548,
AK006371,
U86106,
U86105,
AF044960,
BC028757,
U86107,
U86108
Ensembl:
ENSMUSG00000032271
KO:
mmu:18113
|
| Nucleutide sequences |
EMBL-CDS:
AAB94332.1,
AAB94331.1,
AAB94333.1,
AAH28757.1,
AAC77360.1,
AAB94334.1,
BAB24553.1
Ensembl_TRS:
ENSMUST00000034808,
ENSMUST00000119426
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034808,
ENSMUSP00000112381
RefSeq:
XP_011240719.1,
XP_006510140.1,
NP_001297991.1,
XP_036010576.1,
NP_035054.1
|
| Others |
UniRef100:
UniRef100_D3YX59,
UniRef100_O55239
UniRef90:
UniRef90_O55239,
UniRef90_D3YX59
UniRef50:
UniRef50_P40936,
UniRef50_D3YX59
UniGene:
Mm.8362,
Mm.458542
CCDS:
CCDS23157.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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