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18109 Mycn

18109

Mycn

v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived

protein-coding

Mus musculus

基因描述

Type Description
Definition v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived

研究结论

Date Results Publications
2021-04-17 13:16:00 MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity. 32820040
2020-06-06 12:45:00 Authors identified a panel of genes with altered expression in Th-MYCN/Casp2(-/-) tumors that are strongly associated with neuroblastoma outcome, with roles in melanogenesis, Wnt and Hippo pathway signaling, that also contribute to neuronal differentiation. 30670683
2019-12-14 10:27:00 Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. 30389914
2019-10-26 10:37:00 cardiomyocytes compete according to their combined Myc and Mycn levels and that cell competition eliminates flawed cardiomyocytes, suggesting its relevance as a quality control mechanism in cardiac development. 30642836
2019-09-14 12:00:00 MYCN drives glutaminolysis in neuroblastoma and confers sensitivity to a reactive oxygen species-augmenting agent. 29445162

名称对应

Type IDs
Synonymous N-myc, Nmyc, Nmyc-1, Nmyc1, bHLHe37, c-nmyc
Gene
UniProtKB-ID: MYCN_MOUSE, Q3UII1_MOUSE
UniprotKB: P03966, Q3UII1
UniParc: UPI0000025914
EMBL: AK146913, AK146696, M29208, M12731, M36277, X06993, X03919
Ensembl: ENSMUSG00000037169
KO: mmu:18109
Nucleutide sequences
EMBL-CDS: AAA39833.1, CAA27557.1, AAA39788.1, AAA39830.1, BAE27366.1, BAE27525.1
Ensembl_TRS: ENSMUST00000130990, ENSMUST00000043396
Protein sequencees
Ensembl_PRO: ENSMUSP00000045993, ENSMUSP00000114225
RefSeq: NP_032735.3
Others
UniRef100: UniRef100_P03966
UniRef90: UniRef90_P03966
UniRef50: UniRef50_P03966
UniGene: Mm.16469
CCDS: CCDS25818.1

全选

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