ksr-1 - Kinase suppressor of Ras A-BMKCloudï½ç¾è¿å®¢äº

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181082 ksr-1

基因描述

Type	Description
Definition	Kinase suppressor of Ras A

研究结论

Date	Results	Publications
2018-10-06 11:18:00	KSR-1 modulates locomotion downstream of, or in parallel to, the Gq-Rho pathway.	29615470
2010-01-21 00:00:00	Review highlights the implication of CNK and KSR in a novel mechanism regulating RAS-mediated RAF activation.	17496912

名称对应

Type	IDs
Gene	UniProtKB-ID: KSRA_CAEEL UniprotKB: G5EFD2 UniParc: UPI0000078E3D EMBL: U38820, BX284606, S80647 EnsemblGenome: WBGene00002239 KO: cel:CELE_F13B9.5
Nucleutide sequences	EMBL-CDS: AAB35769.1, CCD69410.1, AAA92436.1 Gene_ORFName: F13B9.5 EnsemblGenome_TRS: F13B9.5.1, F13B9.5.2
Protein sequencees	EnsemblGenome_PRO: F13B9.5.1, F13B9.5.2 RefSeq: NP_509396.1
Others	UniRef100: UniRef100_G5EFD2 UniRef90: UniRef90_G5EFD2 UniRef50: UniRef50_G5EFD2 UniGene: Cel.11005

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
31308550	EPIC: software toolkit for elution profile-based inference of protein complexes. Nat Methods Lucas ZhongMing Hu , Florian Goebels , June H Tan , Eric Wolf , Uros Kuzmanov , Cuihong Wan , Sadhna Phanse , Changjiang Xu , Mike Schertzberg , Andrew G Fraser , Gary D Bader , Andrew Emili	2019-08-01	-
29615470	Modulation of Gq-Rho Signaling by the ERK MAPK Pathway Controls Locomotion in Caenorhabditis elegans. Genetics Brantley Coleman , Irini Topalidou , Michael Ailion	2018-06-01	-
23900546	The NM23-H1/H2 homolog NDK-1 is required for full activation of Ras signaling in C. elegans. Development Neda Masoudi , Luca Fancsalszky , Ehsan Pourkarimi , Tibor Vellai , Anita Alexa , Attila RemÃ©nyi , Anton Gartner , Anil Mehta , Krisztina TakÃ¡cs-Vellai	2013-08-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
17496912	KSR and CNK: two scaffolds regulating RAS-mediated RAF activation. Oncogene A ClapÃ©ron , M Therrien	2007-05-14	ksr-1, cnk-1, cnk, ksr, CNKSR1
17897480	A global analysis of genetic interactions in Caenorhabditis elegans. J. Biol. Alexandra B Byrne , Matthew T Weirauch , Victoria Wong , Martina Koeva , Scott J Dixon , Joshua M Stuart , Peter J Roy	2007-01-01	mex-3, vps-20, did-2, pop-1, col-48, ftn-2, T20F5.6, unc-73, lin-44, let-502, atp-3, unc-40, cpb-3, lin-35, pnk-1, cdc-25.1, mei-2, cye-1, glh-1, sem-4, lrp-1, ego-1, gld-1, cyc-1, cfim-1, gska-3, sup-17, spd-2, aph-1, ikb-1, sur-6, cco-1, mom-5, fog-3, aph-2, lam-3, hsf-1, par-6, vps-25, gsk-3, F22G12.4, vps-28, pry-1, hmp-2, sur-2, vab-19, ZK546.14, vps-24, mog-5, cpb-2, sma-6, icd-1, vps-32.1, dpy-10, dpy-2, egl-27, B0252.1, tra-2, sod-1, cki-1, mig-5, dab-1, zyg-9, prx-5, let-23, mel-11, kin-15, mex-6, ptp-3, unc-53, unc-130, F54D5.5, lin-29, sop-2, hpr-17, lin-7, mog-4, unc-52, par-2, daf-2, cri-3, clpf-1, npp-9, F59A2.5, C34C12.8, M01F1.8, pitp-1, rpl-37, nhr-6, sel-8, rilp-1, unc-93, C46F11.5, C46F11.4, npr-15, pdi-1, dph-1, alkb-8, C14B1.9
16845399	Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways. Nat. Genet. Ben Lehner , Catriona Crombie , Julia Tischler , Angelo Fortunato , Andrew G Fraser	2006-08-01	his-40, egl-30, sop-3, unc-73, let-502, rnt-1, lin-35, gpc-2, swsn-9, pbrm-1, goa-1, ego-1, apr-1, kin-10, unc-120, ceh-6, cdk-8, aph-1, irx-1, sur-6, nhr-49, mom-5, csnk-1, rga-2, gsk-3, pry-1, hmp-2, sur-2, ptr-23, hlh-1, vab-1, tsn-1, fbf-1, fbf-2, rars-2, lin-23, egl-27, cdc-42, lir-1, B0495.2, spv-1, qua-1, jun-1, let-23, ref-1, ptp-3, din-1, trr-1, lin-29, ace-4, unc-52, nhr-80, attf-3, mat-3, swsn-3, nhr-6, mtm-3, cdk-12, ndg-4, mel-28, abi-1, hmg-1.2, algn-1, T26A5.8, ubc-18, lin-37, zfp-1, pat-2, lin-12, glp-1, gei-13, ham-3, pha-1, nob-1, set-16, tpa-1, efn-4, egl-18, ced-10, nstp-6, vab-2, hlh-30, htz-1, eor-1, lag-1, lin-45, nhr-8, F33D4.6, arf-3, hgrs-1, nhr-66, nap-1, pkg-2, F49C12.12, F49C12.11, lin-3, kin-4, let-60, par-5
15268855	The ERK MAP kinase cascade mediates tail swelling and a protective response to rectal infection in C. elegans. Curr. Biol. Hannah R Nicholas , Jonathan Hodgkin	2004-07-27	mek-2, sur-2, mpk-1, lin-45, lin-25, ksr-1
11882296	C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation. Curr. Biol. Mitsue Ohmachi , Christian E Rocheleau , Diane Church , Eric Lambie , Tim Schedl , Meera V Sundaram	2002-03-05	-
10409742	Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization. Mol Cell Biol S Stewart , M Sundaram , Y Zhang , J Lee , M Han , K L Guan	1999-08-01	-

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